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Report of the Independent Panel on the U.S. Department of Health and Human Services (HHS) Ebola Response

                    

disasterlit.nlm.nih.gov - June 30, 2016

This 57-page report summarizes a request to capture critical lessons from the Ebola epidemic of 2014-2016 and review the Department of Health and Human Services (HHS)'s international and domestic responses. It summarizes an Independent Panel's assessment of HHS's challenges, and, where appropriate, challenges facing the broader U.S. government. It describes notable opportunities for improvement in leadership and organization, communication, management, and logistics, as well as in development and use of vaccines and treatments. It also presents recommendations for addressing future urgent public health threats.

CLICK HERE - ADDITIONAL INFORMATION AND ACCESS TO THE REPORT - Report of the Independent Panel on the U.S. Department of Health and Human Services (HHS) Ebola Response

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CLICK HERE - ADDITIONAL INFORMATION AND ACCESS TO THE REPORT - Report of the Review Committee on the Role of the International Health Regulations (2005) in the Ebola Outbreak and Response

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Ibuprofen 'Disables' Ebola Virus

SPL

CLICK HERE - RESEARCH - Nature - Toremifene interacts with and destabilizes the Ebola virus glycoprotein

bbc.com - by James Gallagher - June 30, 2016

The painkiller ibuprofen and the cancer drug toremifene can disable the Ebola virus, say researchers.

Scientists used the UK's national synchrotron facility - Diamond Light Source - to analyse the virus in incredible detail.

They revealed the two drugs could bind to the crucial part of Ebola that the virus needs to infect cells.

However, the team warns this is just a starting point and more effective drugs need to be researched.

(READ COMPLETE ARTICLE)

ADDITIONAL REFERENCES ARE PROVIDED BELOW:

Toremifene interacts with and destabilizes the Ebola virus glycoprotein
http://www.nature.com/nature/archive/subject.html?code=326

Toremifene interacts with and destabilizes the Ebola virus glycoprotein
http://www.nature.com/subjects/ebola-virus

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Researchers look to repurpose approved drugs to treat Zika virus

published by 

6:47 p.m. EDT May 2, 2016

ATLANTA — The need for drugs to prevent and treat Zika infections grows with every new patient diagnosed. The virus causes devastating birth defects and is strongly linked to a type of paralysis called Guillain-Barre syndrome.

There are currently no approved drugs against Zika; developing a new medication for any disease can take 10 to 20 years.

"The sense of urgency is enormous," said Mauro Martins Teixeira, who heads the immunopharmacology laboratory at the Federal University of Minas Gerais in Brazil. "In an emergency, everyone wants quick answers."

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A Billion in Pandemic Prevention Is Worth a Trillion in Cure

          

Photographer: Waldo Swiegers /Bloomberg

The world is warned to prepare now for health crises such as the Ebola outbreak, or pay a lot more later.

CLICK HERE - LINK TO REPORT AND OTHER IMPORTANT INFORMATION - The Neglected Dimension of Global Security - A Framework to Counter Infectious Disease Crises 

bloomberg.com - by John Tozzi - January 13, 2016

The world needs a . . . transformation to prevent outbreaks of infectious disease that threaten security and economic stability, according to a report sponsored by several major foundations. Pandemics—epidemics that spread across the globe—could cost humanity $6 trillion in the 21st century, or $60 billion a year, the authors estimate. They argued for investing $4.5 billion a year—or 65 cents for every resident of the planet—to prepare.

(READ COMPLETE ARTICLE)

 

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The Neglected Dimension of Global Security - A Framework to Counter Infectious Disease Crises

nam.edu - January 13, 2016

CLICK HERE - National Academy of Medicine - Global Health Risk Framework - The Neglected Dimension of Global Security: A Framework to Counter Infectious Disease Crises

CLICK HERE - REPORT - The Neglected Dimension of Global Security: A Framework to Counter Infectious Disease Crises (144 page .PDF report)

The Global Health Risk Framework (GHRF) initiative will build on lessons from the current Ebola outbreak and other major outbreaks to develop a comprehensive framework for improving our response to future global public health threats. The Commission will rigorously analyze options for improving governance, finance, health system resilience, and research and development for global health security. To foster trust internationally with various levels of government, civil society, academia, and industry, the Commission intends to keep the framework from being influenced by politics or the interests of any one country or organization.

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How Post-Ebola Syndrome is Making Life Difficult After the Dreaded Disease

submitted by Gavin Macgregor-Skinner

Al Jazeera America - (Tonight) Thursday, Jan 14, 2016 at 930pm EST 

Survivors of Ebola report strange symptoms as America Tonight examines how post-Ebola syndrome is making life difficult after the dreaded disease. (new, 30 minutes)

CLICK ON THE LINK BELOW - Watch at 930pm EST on Thursday, Jan 14, 2016
http://america.aljazeera.com/watch/shows/america-tonight.html

 

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This is How We Got to Zero Ebola Cases in West Africa:

whitehouse.gov - by Amy Pope - December 30, 2015

Summary: The world has now gone over 40 consecutive days without a single reported Ebola case. Here's how we helped make that possible.

For the first time since this outbreak was detected in West Africa in early 2014, the world has now gone over 40 consecutive days without a single reported Ebola case.

The World Health Organization (WHO) announced that Guinea has successfully halted Ebola transmission and now joins Sierra Leone and Liberia in recovering from this devastating disease. This represents a significant milestone for Guinea, West Africa, and the international community.

Today we reflect on what is possible when partners around the world come together to solve a common problem. Through the undaunted courage of local communities and heroes from around the world, West Africa was able to halt Ebola. The United States was proud to offer help along with partners around the world.

Today we remember Ebola’s victims, and embrace the communities, families, healthcare workers, and survivors.

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Preparing for the Next Ebola - The Year In Review

submitted by George Hurlburt

             

Caught off guard in 2014, health care regrouped and reorganized in 2015.  (Photo: Romeo Ranoco/Reuters)

takepart.com - by Hannah Hoag - December 14, 2015

As horrific images of bodies piling up in West Africa and stories of children orphaned by Ebola filled American media over the summer and early fall of 2014, many feared someone with the virus would arrive undetected in the U.S. and spur a major outbreak. But experts considered the risk of that happening to be very low, says Kamran Khan, an infectious disease physician at St. Michael’s Hospital in Toronto and the founder of BlueDot, a social enterprise that uses big data to mitigate the impacts of global infectious disease. . . .

. . . Yet in October 2014, Thomas Eric Duncan was admitted to a Dallas hospital with Ebola shortly after arriving in the U.S. from Liberia.

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Guinea’s Ebola Outbreak is Declared Officially Over

submitted by George Hurlburt / Mike Kraft

An MSF health worker holds baby Nubia Souma, the last known Ebola patient in Guinea.  Image: Samuel Aranda/MSF

CLICK HERE - WHO - STATEMENT - End of Ebola transmission in Guinea

(ALSO SEE SITUATION REPORTS AND RELATED ARTICLE BELOW)

Forty-two days have passed since the last person with Ebola tested negative for the virus.

thejournal.ie - by Sinead O'Carroll - December 29, 2015

THE WORLD HEALTH Organisation has declared the Ebola outbreak in Guinea officially over.

In a statement this morning, the global body confirmed that 42 days had passed since the last person with Ebola in the country tested negative for the virus for a second time.

Guinea will now enter a 90-day period of “heightened surveillance” to ensure any new cases are identified before being passed on to other people.

(READ COMPLETE ARTICLE)

(CLICK HERE - SEE RELATED ARTICLE)

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Report Finds Major Gaps in Country’s Ability to Prevent and Control Infectious Disease Outbreaks

CLICK HERE - REPORT - Outbreaks: Protecting Americans from Infectious Diseases

CLICK HERE - REPORT - Outbreaks: Protecting Americans from Infectious Diseases (116 page .PDF report)

healthyamericans.org - Press Release - December 17, 2015

28 States and Washington, D.C. Reach Half or Fewer of Key Indicators

Washington, D.C., December 17, 2015 – A new report released today found that more than half (28) of states score a five or lower out of 10 key indicators related to preventing, detecting, diagnosing and responding to outbreaks.   The report, from Trust for America’s Health (TFAH) and the Robert Wood Johnson Foundation (RWJF), concluded that the United States must redouble efforts to better protect the country from new infectious disease threats, such as MERS-CoV and antibiotic-resistant superbugs, and resurging illnesses like whooping cough, tuberculosis and gonorrhea.

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