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Ivermectin still nopt a good COVID-19 Treatment--large new trial

Ivermectin: Still on a Losing Streak as COVID-19 Treatment | MedPage Today

WASHINGTON -- There were no differences in relief from mild-to-moderate COVID-19 symptoms for patients on ivermectin versus placebo, according to the ongoing ACTIV-6 trial.

Among >1,000 vaccinated and unvaccinated patients, the median time to recovery was 12 days for those in the ivermectin group and 13 days in the placebo group, reported Matthew McCarthy, MD, of Weill Cornell Medicine in New York City, at IDWeek.

As a result, the hazard ratio for improvement in time to recovery was 1.07 (95% credible interval 0.96-1.17, posterior P=0.91), McCarthy and colleagues stated in JAMA, where the results were simultaneously published.

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Ebola: Uganda applies lessons from first outbreak, but reports increase in the capital

Uganda applies well-honed lessons to new Ebola outbreak (nbcnews.com)

...the East African country — lauded for its coronavirus response, which was built around engaging the community and training health officials — is drawing lessons from the first Ebola outbreak in 2004.

ALSO SEE: Uganda reports worrisome increase in Ebola cases in capital

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Monkeypox--SIx persons in the U.S. who tested positive have died

Six people who tested positive for monkeypox have died, health departments confirm | CNN

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The two Chicagoans who died after testing positive for monkeypox had multiple other health conditions, including weakened immune systems, according to the Chicago Department of Health (CDPH).

“Though the number of new MPV cases has declined substantially since summer, this is a stark reminder that MPV is dangerous and can cause serious illness, and in very rare cases, even death,” said CDPH Commissioner Dr. Allison Arwady.

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Biden to get updated COVID vaccine, urge Americans to follow suit

Biden to get updated COVID vaccine, urge Americans to follow suit | Reuters

 (Reuters) - U.S. President Joe Biden will get his updated COVID-19 vaccine on Tuesday and urge more Americans to get the latest shot, White House spokesman Kevin Munoz said on Sunday.

Only 20 million people in the United States have received an updated COVID vaccine through last week. White House spokeswoman Karine Jean-Pierre said on Thursday it was not enough.

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Omicron subvariants pose a new threat to people with immune deficiencies

Omicron subvariants pose a new threat to people with immune deficiencies (nbcnews.com)

New versions of the omicron virus show resistance to the antibody drugs many need for extra protection against Covid.

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People with compromised immune systems face a new winter of discontent as the ever-mutating omicron virus threatens to outrun the preventive monoclonal antibody cocktail that hundreds of thousands of them have relied upon for extra protection against Covid.

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Analysis: The main COVID symptoms have changed-- new research

The main COVID symptoms have changed, research shows | The Hill

 ... like all viruses, the primary symptoms associated with COVID have changed and can vary based on your vaccination status, according to a new list released last week.

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Researchers have found that for participants in all three groups — fully vaccinated, those who received just one dose, and unvaccinated — four of the five most commonly reported symptoms are the same: sore throat, runny nose, persistent cough, and headache.

Their prevalences across the groups, however, vary, as does the fifth symptom.

For those who are vaccinated, a blocked nose is the third-most frequently reported symptom. Among the partially vaccinated, it’s sneezing, and the unvaccinated, fever.

Below are the symptoms most commonly reported among the three groups, ranked in order of how often they are reported.  ...

 

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A ‘Tripledemic’? Flu and Other Infections Return as Covid Cases Rise

A ‘Tripledemic’? Flu and Other Infections Return as Covid Cases Rise - The New York Times (nytimes.com)

 

For more than two years, shuttered schools and offices, social distancing and masks granted Americans a reprieve from flu and most other respiratory infections. This winter is likely to be different.

With few to no restrictions in place and travel and socializing back in full swing, an expected winter rise in Covid cases appears poised to collide with a resurgent influenza season, causing a “twindemic” — or even a “tripledemic,” with a third pathogen, respiratory syncytial virus, or R.S.V., in the mix.

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