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County Health Director: Count on More Zika-Related Birth Defects

submitted by Albert Gomez

The Zika-carrying Aedes aegypti mosquito is photographed through a microscope. (AP Photo/Felipe Dana, File)

CLICK HERE - REPORT - CDC - Vital Signs: Update on Zika Virus–Associated Birth Defects and Evaluation of All U.S. Infants with Congenital Zika Virus Exposure — U.S. Zika Pregnancy Registry, 2016

mypalmbeachpost.com - by John Pacenti - April 8, 2017

Sick of hearing about Zika already? Get used to it as more birth defects related to the virus are expected in 2017 in Florida and throughout the U.S.

This summer, there will be a full-court press by health officials against Zika.

“It’s not something to be taken lightly,” said Dr. Alina Alonso, head of the Palm Beach County Health Department, in an interview with The Palm Beach Post.

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Zika Could End Up Costing Latin America and the Caribbean Up To $18 Billion, UN Reports Finds

                           

CLICK HERE - REPORT - A Socio-economic Impact Assessment of the Zika Virus in Latin America and the Caribbean: with a focus on Brazil, Colombia and Suriname

un.org

6 April 2017 – In addition to the impact on public health, the tangible impact of the Zika outbreak, such as on gross domestic product (GDP), could cost the Latin American and the Caribbean region as much as $18 billion between 2015 and 2017, a new United Nations report has revealed.

The report Socio-economic impact assessment of Zika virus in Latin America and the Caribbean, prepared by the UN Development Programme (UNDP) in partnership with the International Federation of Red Cross and Red Crescent Societies (IFRC), has a particular focus on Brazil, Colombia and Suriname – countries that first reported the outbreak in October-November 2015.

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One in 10 Pregnant Women With Zika in U.S. Have Babies With Birth Defects

submitted by Albert Gomez

CLICK HERE - CDC - MMWR - Vital Signs: Update on Zika Virus–Associated Birth Defects and Evaluation of All U.S. Infants with Congenital Zika Virus Exposure — U.S. Zika Pregnancy Registry, 2016

nytimes.com - by Pam Belluck - April 4, 2017

One in 10 pregnant women in the continental United States with a confirmed Zika infection had a baby with brain damage or other serious birth defects, according to the most comprehensive report to date on American pregnancies during the Zika crisis.

The report, published Tuesday by the Centers for Disease Control and Prevention, also provided more evidence that the risk of birth defects was greater when women were infected in the first trimester of pregnancy. Fifteen percent of women with confirmed Zika infection in the first trimester had babies with birth defects, the report found.

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Dengue May Bring Out the Worst in Zika

           

Brazilian soldiers last year led a battle against Zika in a door-to-door campaign about how to control mosquitoes that carry the disease.  EVARISTO SA/AFP/GETTY IMAGES

CLICK HERE - Science - Enhancement of Zika virus pathogenesis by preexisting antiflavivirus immunity

sciencemag.org - by Jon Cohen - March 30, 2017

Close relatives have complicated relationships with each other even in the viral world. A new mouse study shows that if the animals have antibodies from dengue or West Nile virus, it sets them up for more severe disease from their close cousin, Zika virus.

If such "antibody-dependent enhancement" (ADE) also takes place in people, it could have helped fuel Zika's recent explosion in Brazil, where more than 90% of people in some communities have been infected with dengue. ADE could also complicate the development of vaccines for West Nile, dengue, and Zika. And with the onset of spring reigniting local transmission of Zika last week in the continental United States—where West Nile is widespread—ADE could give epidemiologists a new window into transmission and disease patterns.

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Why Didn't Zika Cause A Surge In Microcephaly In 2016?

           

A family member holds twins Eloisa (left) and Eloa, both 8 months old and born with microcephaly, during a Christmas gathering. The mother of the twins, Raquel, who lives in Brazil, said she contracted Zika during her pregnancy.  Mario Tama/Getty Images

CLICK HERE - NEJM - Zika Virus Infection and Associated Neurologic Disorders in Brazil

CLICK HERE - Science - Enhancement of Zika virus pathogenesis by preexisting antiflavivirus immunity

npr.org - by Michaeleen Doucleff - March 30, 2017

Back in 2015, Brazil reported a horrific a surge in birth defects. Thousands of babies were born with brain damage and abnormally small heads, a condition called microcephaly.

Scientists quickly concluded the Zika virus was the culprit. So when Zika returned last year during Brazil's summer months of December, January and February — when mosquitoes are most active — health officials expected another surge in microcephaly cases.

But that never happened.

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The Real Threat to National Security: Deadly Disease

Credit Niv Bavarsky

nytimes.com - by MICHAEL T. OSTERHOLM and MARK OLSHAKER
March 24, 2017

While the Trump administration is proposing significantly increased military spending to enhance our national security, it seems to have lost sight of the greatest national security threat of all: our fight against infectious disease.

We already spend far more on our military than any other country in the world. To help pay for the increases, President Trump wants to cut back many federal programs, including those that prepare us to wage war against microbes, the greatest and most lethal enemy we are ever likely to face. This is where “defense spending” needs to increase, significantly.

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Tiny Genetic Change Lets Bird Flu Leap to Humans

           

At least six provinces have reported human cases of H7N9 influenza this year, according to Chinese state media - Getty Images

CLICK HERE - STUDY - Nature Communications - An NS-segment exonic splicing enhancer regulates influenza A virus replication in mammalian cells

bbc.com - March 21, 2017

A change in just a single genetic "letter" of the flu virus allows bird flu to pass to humans, according to scientists.

Monitoring birds for viruses that carry the change could provide early warning of risk to people, they say . . .

 . . . The change in a single nucleotide (a building block of RNA) allows the H7N9 virus to infect human cells as well as birds, say Prof Honglin Chen and colleagues.

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Testing for Zika Virus: There's an App for That

           

Sandia National Laboratories chemical engineer and lead paper author Aashish Priye offers a view into the Zika box prototype, along with co-authors Sara Bird, a virologist, center, and a biomedical engineer.  Credit: Randy Wong

CLICK HERE - Scientific Reports - A smartphone-based diagnostic platform for rapid detection of Zika, chikungunya, and dengue viruses

sciencedaily.com - DOE/Sandia National Laboratories - March 20, 2017 - 

Prototype dramatically cuts cost, time for detection of mosquito-borne illness

Add rapid, mobile testing for Zika and other viruses to the list of things that smartphone technology is making possible. Researchers have developed a smartphone-controlled, battery-operated diagnostic device that weighs under a pound, costs as little as $100 and can detect Zika, dengue and chikungunya within 30 minutes.

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African Strain of Zika Kills Placenta Cells in Days

futurity.org - University of Missouri - posted by Jeff Sossamon - March 9, 2017

CLICK HERE - STUDY - PNAS - Vulnerability of primitive human placental trophoblast to Zika virus

Infection of pregnant women by the Asian strain of Zika virus has been linked to brain abnormalities such as microcephaly in their infants. It’s not clear, however, at what stage of pregnancy the human fetus is most susceptible to the disease.

A new study shows the human fetus may be most vulnerable to Zika infection very early in pregnancy. In addition, the lesser-known African strain of Zika might possibly cause nearly immediate death of the placenta.

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Why Global Warming Could Lead to a Rise of 100,000 Diabetes Cases a Year in the U.S.

           

Global warming could result in more cases of diabetes around the world, a new study suggests. (Mario Tama / Getty Images)

CLICK HERE - STUDY - BMJ Open Diabetes Research & Care - Diabetes incidence and glucose intolerance prevalence increase with higher outdoor temperature

latimes.com - by Karen Kaplan - March 20, 2017

If the average temperature rises by 1 degree Celsius, sea levels will rise, crop yields will fall and vulnerable species will see their habitat shrink or disappear.

And, a new study suggests, the number of American adults suffering from diabetes would rise by more than 100,000 a year.

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CLICK HERE - Is there a link between climate change and diabetes?

CLICK HERE - Rise in diabetes and NCDs linked to climate change

 

 

 

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