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Mission Not Yet Accomplished --Editorial

EDITORIAL: NEW YORK TIMES                                       Feb. 17, 2015
President Obama has announced that almost all of the American troops sent to West Africa to help contain the Ebola epidemic will be withdrawn soon. That makes sense because they have largely completed the work they were sent to do. The next phase of the battle will rely on public health measures carried out by local and international health workers and experts.

Despite major gains, about 100 new cases are detected each week. It will take a concerted effort, backed financially by the United States and others, to drive that number down to zero....

The main task now facing public health workers is to find all people infected with Ebola and trace and isolate all their contacts to prevent passing the virus to others. The goal is to eradicate all traces of the virus from the afflicted countries. A well-trained work force will be essential to this task. As Mr. Obama warned last week, “Every case is an ember that if not contained can light a new fire.”

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http://www.nytimes.com/2015/02/16/opinion/mission-not-yet-accomplished.html

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Ebola: the race to find a cure

 In October, scientists set out to do something unprecedented – conduct a drugs trial during an epidemic to find a treatment for a lethal disease. Could they make history and change the way we deal with outbreaks?

THE GUARDIAN  by Sarah Boseley                           Feb, 17, 2015

In depth description of efforts by a group of Oxford University scientists to run field trials of drugs for use against Ebola.

" ...The little band of scientists had flown to Guinea on 16 October to do something that had never been successfully done before – set up a trial of experimental drugs against an infectious disease in the middle of an epidemic. Because the Ebola virus does not exist at low levels in any population, unless you run a properly conducted trial while the storm is raging, you will never have drugs that are proven to be effective. The Oxford team’s trial would not only aim to find a drug that worked against Ebola but also to establish a blueprint for the way drug trials would be run during outbreaks in the future. This did not just apply to fighting Ebola: if the scientists were successful, their trial would develop protocols for testing drugs for any epidemic, be it Sars or flu...."

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What Liberia needs from donors post-Ebola

DEVEX    by Molly Anders                                                                                                   Feb. 16, 2015

Interview with Liberian Assistant Minister of Health Tolbert Nyenswah about his vision for the development community’s role in a post-Ebola Liberia: 

" Every facet of our society was affected. From women and children to social protections, our economy and financial system; the GDP suffered hugely because of Ebola.
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Obama uses war on Ebola to illustrate fight against non-conventional threats

WASHINGTON POST by Juliet Eilperin and Steven Mufson                             Feb. 13, 2015

WASHINGTON --If there is to be war, the fight against Ebola is President Obama’s type of war. The enemy fires no bullets and carries no bombs; it doesn’t use social media to recruit fighters and rally supporters. And the fighting can best be done by intelligent professionals who don’t try to kill people, but to save them.

On Wednesday, Obama celebrated the progress against the deadly virus since the administration launched a military and civilian effort in September. While the president emphasized it was too soon to declare “mission accomplished” — as President George W. Bush did about Iraq in 2003 — Obama said “we’re shifting our focus from fighting the epidemic to now extinguishing it.”

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Ebola in west Africa: learning the lessons

THE LANCET  by  Anna  Petherick  Volume 385, No. 9968, p591–592, 14 February 2015
The (West Africa) region has presented unforeseen challenges, and the three worst affected countries have put in place different response strategies. Anna Petherick reviews some of the lessons learned so far.

The early history of the ongoing Ebola outbreak in west Africa is a salutary statement about the lack of infectious disease surveillance capacity in one of the world's poorest regions....

Opportunities to contain the virus were lost soon after, largely because of a lack of trust between local communities and the officials and medical professionals trying to nip the epidemic in the bud.

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http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2815%2960075-7/fulltext

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Why Didn't Ebola Kill Me?

An ambulance transports the author to the Nebraska Medical Center in October. (Sait Serkan Gurbuz/Reuters)

THE ATLANTIC by Ashoka Mukpo                                                                          Feb. 12, 2015

Like the majority of patients taken to Western hospitals, I recovered from the disease—but health authorities are still struggling to figure out how to bring up the much-lower survival rate in West Africa.

...the 80-percent survival rate among patients who were evacuated to Western hospitals shattered the idea that an Ebola diagnosis spelled near-certain death. I know this all too well, as I’m one of those patients myself. In October, I contracted Ebola while covering the outbreak as a freelance journalist in Liberia. I was airlifted to a hospital in Nebraska, where aggressive treatment likely saved my life....
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http://www.theatlantic.com/health/archive/2015/02/why-didnt-ebola-kill-me/385335/

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UN: 10,000 US-supported civilians needed to fight Ebola

ASSOCIATED PRESS by Edith M. Leder                                                                          Feb. 11, 2015
UNITED NATIONS (AP) — The U.N. Ebola chief says U.S. troops being withdrawn from Liberia have done their job of building desperately needed treatment centers but that more than 10,000 civilians working in West Africa and supported by the United States are still essential to combating the deadly disease.

Dr. David Nabarro warned in an interview Wednesday with The Associated Press that the battle against Ebola is far from over, pointing to a disappointing rise in new cases last week in hardest-hit Liberia, Sierra Leone and Guinea.

He said civilians from the U.S., Britain, France and elsewhere are still needed to help with tracing Ebola victims' contacts, re-establishing health services and changing behavior in communities.

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http://news.yahoo.com/un-ebola-chief-10-000-us-civilians-needed-183453840.html;_ylt=AwrBJSCfs9xUf00Af7XQtDMD

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'Good virus' believed to help increase survival chances in Ebola and HIV infections

INTERNATIONAL BUSINESS NEWS by Jayalaksmi K      Feb. 2, 2015

A common virus that infects billions at some point of their lives is believed to deliver some protection against other deadlier viruses like HIV and Ebola.

David O'Connor, a pathology professor at the University of Wisconsin in Madison, found the genetic fingerprints of the virus GBV-C in the records of 13 samples of blood plasma from Ebola patients.

While six of the 13 people who were co-infected with Ebola and GBV-C died, seven survived.

Combined with earlier studies that have hinted persistent infection with the virus slowed disease progression in some HIV patients, researchers think the virus could be beneficial.

"We're very cautious about over-interpreting these results," O'Connor told NPR. He is now waiting to get a bigger sample, to see if there really is a strong connection between GBV-C infection and survival.
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Botswana Doctor Is Named to Lead W.H.O. in Africa

NEW YORK TIMES  by Donald G. McNeil, Jr.                                                               Jan. 27, 2015

A defining moment in the life of Dr. Matshidiso Moeti, the World Health Organization’s new regional director for Africa, came when she was 9 and her father realized that her little sister’s mathematics textbook was below even the level he had studied as a poor child on a South African farm.

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Scientists ask if Ebola immunizes as well as kills

LONDON/DAKAR--A recent sharp drop in new Ebola infections in West Africa is prompting scientists to wonder whether the virus may be silently immunizing some people at the same time as brutally killing their neighbors.

A health worker disinfects a road in the Paynesville neighborhood of Monrovia, Liberia, January 21, 2015. Credit: Reuters/James Giahyue

So-called "asymptomatic" Ebola cases - in which someone is exposed to the virus, develops antibodies, but doesn't get sick or suffer symptoms - are hotly disputed among scientists, with some saying their existence is little more than a pipe dream.

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