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New Drugs Found to Cause Side Effects Years After Approval

Abilify - Daniel Acker / Bloomberg via Getty Images

CLICK HERE - RESEARCH - JAMA - Postmarket Safety Events Among Novel Therapeutics Approved by the US Food and Drug Administration Between 2001 and 2010

nbcnews.com - Associated Press - May 10, 2017

Almost one-third of new drugs approved by U.S. regulators over a decade ended up years later with warnings about unexpected, sometimes life-threatening side effects or complications, a new analysis found.

The results covered all 222 prescription drugs approved by the U.S. Food and Drug Administration from 2001 through 2010. The researchers looked at potential problems that cropped up during routine monitoring that's done once a medicine is on the market.

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Infectious Disease Is the Next Big Global Security Risk

The World Is Not Ready for the Next Pandemic

           

John Hackett and Charles Chiu handle Zika samples at the University of California, San Francisco-Abbott Viral Diagnostics and Discovery Center - Cody Pickens for TIME

time.com - by Bryan Walsh - May 4, 2017

 . . . From Ebola in West Africa to Zika in South America to MERS in the Middle East, dangerous outbreaks are on the rise around the world . . . 

 . . . The U.S. Centers for Disease Control and Prevention (CDC) ranks H7N9 as the flu strain with the greatest potential to cause a pandemic--an infectious-disease outbreak that goes global. If a more contagious H7N9 were to be anywhere near as deadly as it is now, the death toll could be in the tens of millions.

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Scientists Say the Pace of Sea Level Rise Has Nearly Tripled Since 1990

           

An iceberg is pictured in the western Antarctic peninsula in March 2016. (Eitan Abramovich/AFP/Getty Images)

CLICK HERE - RESEARCH - PNAS - Reassessment of 20th century global mean sea level rise

washingtonpost.com - by Chris Mooney - May 22, 2017

A new scientific analysis finds that the Earth’s oceans are rising nearly three times as rapidly as they were throughout most of the 20th century, one of the strongest indications yet that a much feared trend of not just sea level rise, but its acceleration, is now underway.

“We have a much stronger acceleration in sea level rise than formerly thought,” said Sönke Dangendorf, a researcher with the University of Siegen in Germany who led the study along with scientists at institutions in Spain, France, Norway and the Netherlands.

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Solving the Problem of Food Waste

                         

washingtonpost.com

The statistics are sobering: In the United States, 63 million tons of food are wasted every year.  Food waste accounts for 21 percent of all fresh water used in the United States, and takes up 21 percent of landfill volume.  Waste happens at every stage of the supply chain between farm and table.

With this in mind, Sub-Zero launched Fresh Food Matters, an initiative to empower people to think fresh about the food they eat - and to educate and inspire them on food’s far-reaching impact.  The first article in this series explored some of these causes in depth, and we look here at effective, actionable solutions.

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CLICK HERE - Food Cowboy

CLICK HERE - Zero Percent

CLICK HERE - Fresh Food Matters

 

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New Zika Virus Inhibitor Identified

CLICK HERE - RESEARCH - Characterization of the Zika virus two-component NS2B-NS3 protease and structure-assisted identification of allosteric small-molecule antagonists

business-standard.com - ANI - May 17, 2017

A new research has brought a drug to treat Zika infections closer to reality.

The team led by Alexey Terskikh and Alex Strongin from Sanford Burnham Prebys Medical Discovery Institute (SBP) discovered a compound that prevents the virus from spreading.

"We identified a small molecule that inhibits the Zika virus protease, and show that it blocks viral propagation in human cells and in mice," Terskikh said. "Anti-Zika drugs are desperately needed. The fact that the compound seems to work in vivo is really promising, so we plan to use it as a starting point to make an even more potent and effective drug."

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Are Solar and Wind Really Killing Coal, Nuclear and Grid Reliability?

           

Lessons from the Lone Star State: A surge in wind power on the Texas grid didn’t cause reliability problems (and brought down electricity prices) because regulators improved the efficiency of wholesale electricity markets. Sarah Fields Photography/Shutterstock.com

theconversation.com - by Joshua D. Rhodes, Michael E. Webber, Thomas Deetjen and Todd Davidson - May 11, 2017

U.S. Secretary of Energy Rick Perry in April requested a study to assess the effect of renewable energy policies on nuclear and coal-fired power plants.

Some energy analysts responded with confusion, as the subject has been extensively studied by grid operators and the Department of Energy’s own national labs. Others were more critical, saying the intent of the review is to favor the use of nuclear and coal over renewable sources.

So, are wind and solar killing coal and nuclear? Yes, but not by themselves and not for the reasons most people think. Are wind and solar killing grid reliability? No, not where the grid’s technology and regulations have been modernized. In those places, overall grid operation has improved, not worsened.

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2016: A Historic Year for Billion-Dollar Weather and Climate Disasters in U.S.

           

CLICK HERE - NCDC - NOAA - Billion-Dollar Weather and Climate Disasters: Overview

climate.gov - by Adam B. Smith - January 9, 2017

NOAA’s National Centers for Environmental Information (NCEI) tracks U.S. weather and climate events that have great economic and societal impacts (www.ncdc.noaa.gov/billions). Since 1980, the U.S. has sustained 203 weather and climate disasters where the overall damage costs reached or exceeded $1 billion (including adjustments based on the Consumer Price Index, as of January 2017). The cumulative costs for these 203 events exceed $1.1 trillion.

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Chicago Just Posted All the Climate Data Deleted by Trump’s EPA

CLICK HERE - City of Chicago - Climate Change - United States Environmental Protection Agency

grist.org - by Kate Yoder - May 8, 2017

The EPA’s climate change webpage was taken down for revisions last month to “reflect EPA’s priorities under the leadership of President Trump and Administrator Pruitt.” It’s apparently still being updated. (We checked, so you don’t have to.)

The page — which explained the basics of climate science and how it affects us — now has a new home: The City of Chicago’s website.

“Here in Chicago, we know climate change is real, and we will continue to take action to fight it,” reads a statement city officials added to what is essentially a direct facsimile of what was once on the EPA’s site.

An archived “Jan. 19 snapshot”  of the climate science page is still linked on the EPA site, but there’s one tiny problem: As Climate Central reported, the archive is missing information.

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US May Be Severely Underestimating Zika's Potential Impact; Costs Could Be in the Billions

Deadly carriers of disease: Aedes aegypti mosquitoes.  Paulo Whitaker | Reuters

Gulf Coast region is vulnerable to Zika attacks

Congress may not appreciate full extent of potential damage

Conservative calculations suggest full impact could exceed $2 billion

CLICK HERE - PLOS - The potential economic burden of Zika in the continental United States

cnbc.com - by Robert Ferris - May 11, 2017

The Zika virus stands to cost the United States billions of dollars, even if few people are infected.

Researchers from several American institutions have calculated that the "virus from Hell" could result in total costs ranging from $183 million to over $1.2 billion, depending on infection rates in several at-risk states in the South.

The researchers warn that infection rates could engender costs that exceed the amounts of money the U.S. government may give for prevention and treatment, if the recent debates over funding are any indication.

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Zika Testing Recommendations Changed for Pregnant Women

           

A nurse practitioner gives a pregnant woman insecticide and information about Zika at a Miami clinic last summer.  LYNNE SLADKY/AP

CLICK HERE - CDC - Health Alert Network (HAN) - Prolonged IgM Antibody Response in People Infected with Zika Virus: Implications for Interpreting Serologic Testing Results for Pregnant Women

statnews.com - by Helen Branswell - May 5, 2017

 . . . Testing for Zika infection is becoming more difficult, making it harder for doctors to advise pregnant women about the chances their child might have a Zika-related birth defect, the Centers for Disease Control and Prevention revealed in a health advisory issued Friday.

The CDC is now suggesting that women thinking of getting pregnant, and who may be exposed to the Zika virus through travel or because of where they live, should consider having their blood tested for Zika antibodies before they get pregnant. Having a baseline reading would help to interpret Zika tests done during a later pregnancy.

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