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Report of the Independent Panel on the U.S. Department of Health and Human Services (HHS) Ebola Response

                    

disasterlit.nlm.nih.gov - June 30, 2016

This 57-page report summarizes a request to capture critical lessons from the Ebola epidemic of 2014-2016 and review the Department of Health and Human Services (HHS)'s international and domestic responses. It summarizes an Independent Panel's assessment of HHS's challenges, and, where appropriate, challenges facing the broader U.S. government. It describes notable opportunities for improvement in leadership and organization, communication, management, and logistics, as well as in development and use of vaccines and treatments. It also presents recommendations for addressing future urgent public health threats.

CLICK HERE - ADDITIONAL INFORMATION AND ACCESS TO THE REPORT - Report of the Independent Panel on the U.S. Department of Health and Human Services (HHS) Ebola Response

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CLICK HERE - ADDITIONAL INFORMATION AND ACCESS TO THE REPORT - Report of the Review Committee on the Role of the International Health Regulations (2005) in the Ebola Outbreak and Response

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Ibuprofen 'Disables' Ebola Virus

SPL

CLICK HERE - RESEARCH - Nature - Toremifene interacts with and destabilizes the Ebola virus glycoprotein

bbc.com - by James Gallagher - June 30, 2016

The painkiller ibuprofen and the cancer drug toremifene can disable the Ebola virus, say researchers.

Scientists used the UK's national synchrotron facility - Diamond Light Source - to analyse the virus in incredible detail.

They revealed the two drugs could bind to the crucial part of Ebola that the virus needs to infect cells.

However, the team warns this is just a starting point and more effective drugs need to be researched.

(READ COMPLETE ARTICLE)

ADDITIONAL REFERENCES ARE PROVIDED BELOW:

Toremifene interacts with and destabilizes the Ebola virus glycoprotein
http://www.nature.com/nature/archive/subject.html?code=326

Toremifene interacts with and destabilizes the Ebola virus glycoprotein
http://www.nature.com/subjects/ebola-virus

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Researchers Develop Model that Predicts Outbreaks of Zoonotic Diseases

Spatial distribution of simulated LAS spill-over events across its endemic region in western Africa for (a) present day, and (b) projected for 2070 under a medium climate and full land cover change scenario. Values represent the expected number of spill-over events per grid cell per year, and are represented on a linear color scale where green is all simulations and grey zero. Axis labels indicate degrees, in a World Geodetic System 84 projection. Filled black circles represent locations of historic LAS outbreaks.  Credit: Redding et al. UCL

CLICK HERE - Predicting disease outbreaks using environmental changes

sciencedaily.com - June 13, 2016

A model that predicts outbreaks of zoonotic diseases -- those originating in livestock or wildlife such as Ebola and Zika -- based on changes in climate, population growth and land use has been developed by a team of researchers.

CLICK HERE -UCL - Predicting disease outbreaks using environmental changes

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4 reasons we're seeing more infectious disease outbreaks around the world

MERS, H1N1, swine flu, chikungunya, Zika: Another virus with a peculiar name always seems to be right around the corner, threatening to become a pandemic.

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Travel clinics try to ease threat of disease

As summer vacation nears, thousands of central Ohioans are planning a trip to an exotic locale -- perhaps to Brazil for the Summer Olympics.

Some doctors warn, however, there are more than sandy beaches, crystal blue waters and margaritas waiting for you: Dangerous parasites, viruses and bacteria can ruin your vacation -- or worse.

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Metagenomics pathogen detection tool could change how infectious diseases are diagnosed

Infectious diseases are one of the biggest killers in the world. Almost 5 million children under age 5 die each year from infectious diseases worldwide, yet many infections are treatable if the pathogen culprit can be quickly and accurately identified.

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Disease Evolution: How New Illnesses Emerge When We Change How We Live

Humans have been “acquiring” infectious diseases from animals (zoonotic diseases) since we first started hunting wild game on the African savannahs. Indeed, nearly 60% of bugs that infect humans originated in animals.

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Beautiful New Images of Ebola Virus and Other Pathogens

When I told her that I wanted to major in microbiology, my best friend from childhood responded, “Are you sure you want to look in a microscope all day?”

But, as it turned out, a lot of microbiologists don’t use microscopes very often. I was one of them. The reason is because a substantial proportion of modern microbiology research uses the tools of molecular biology, for which microscopes are not needed.

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Company calls on FDA to issue permit for genetically modified mosquitoes

 

  A company with a swarm of genetically modified mosquitoes wants   the Food and Drug Administrationto grant emergency approval for   the controversial insects' use in the fight against the Zika virus.

 Oxitec changed the DNA of the Aedes aegypti mosquitoes that    spread the virus so their offspring die before adulthood, Hadyn  Parry, the British company's CEO, told the House of    Representatives' Committee on Science, Space, and Technology in Washington on Wednesday. The company deploys only male mosquitoes, which cannot bite, to halt transmission of the disease, he added.

"I don’t think time is on our side with Zika," Parry said.

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Resilient Health Systems Can Prevent and Contain Pandemics

Resilience is one of those buzzwords that every so often captures the hearts and minds of development practitioners. The importance of this particular term, though, becomes all too clear as the world faces an increasing number of humanitarian crises, including outbreaks that can turn into pandemics.

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