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Report of the Independent Panel on the U.S. Department of Health and Human Services (HHS) Ebola Response

                    

disasterlit.nlm.nih.gov - June 30, 2016

This 57-page report summarizes a request to capture critical lessons from the Ebola epidemic of 2014-2016 and review the Department of Health and Human Services (HHS)'s international and domestic responses. It summarizes an Independent Panel's assessment of HHS's challenges, and, where appropriate, challenges facing the broader U.S. government. It describes notable opportunities for improvement in leadership and organization, communication, management, and logistics, as well as in development and use of vaccines and treatments. It also presents recommendations for addressing future urgent public health threats.

CLICK HERE - ADDITIONAL INFORMATION AND ACCESS TO THE REPORT - Report of the Independent Panel on the U.S. Department of Health and Human Services (HHS) Ebola Response

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CLICK HERE - ADDITIONAL INFORMATION AND ACCESS TO THE REPORT - Report of the Review Committee on the Role of the International Health Regulations (2005) in the Ebola Outbreak and Response

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Ibuprofen 'Disables' Ebola Virus

SPL

CLICK HERE - RESEARCH - Nature - Toremifene interacts with and destabilizes the Ebola virus glycoprotein

bbc.com - by James Gallagher - June 30, 2016

The painkiller ibuprofen and the cancer drug toremifene can disable the Ebola virus, say researchers.

Scientists used the UK's national synchrotron facility - Diamond Light Source - to analyse the virus in incredible detail.

They revealed the two drugs could bind to the crucial part of Ebola that the virus needs to infect cells.

However, the team warns this is just a starting point and more effective drugs need to be researched.

(READ COMPLETE ARTICLE)

ADDITIONAL REFERENCES ARE PROVIDED BELOW:

Toremifene interacts with and destabilizes the Ebola virus glycoprotein
http://www.nature.com/nature/archive/subject.html?code=326

Toremifene interacts with and destabilizes the Ebola virus glycoprotein
http://www.nature.com/subjects/ebola-virus

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Researchers Develop Model that Predicts Outbreaks of Zoonotic Diseases

Spatial distribution of simulated LAS spill-over events across its endemic region in western Africa for (a) present day, and (b) projected for 2070 under a medium climate and full land cover change scenario. Values represent the expected number of spill-over events per grid cell per year, and are represented on a linear color scale where green is all simulations and grey zero. Axis labels indicate degrees, in a World Geodetic System 84 projection. Filled black circles represent locations of historic LAS outbreaks.  Credit: Redding et al. UCL

CLICK HERE - Predicting disease outbreaks using environmental changes

sciencedaily.com - June 13, 2016

A model that predicts outbreaks of zoonotic diseases -- those originating in livestock or wildlife such as Ebola and Zika -- based on changes in climate, population growth and land use has been developed by a team of researchers.

CLICK HERE -UCL - Predicting disease outbreaks using environmental changes

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Disease Evolution: How New Illnesses Emerge When We Change How We Live

Humans have been “acquiring” infectious diseases from animals (zoonotic diseases) since we first started hunting wild game on the African savannahs. Indeed, nearly 60% of bugs that infect humans originated in animals.

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White House to transfer Ebola funds to combat Zika virus

WASHINGTON (AP) — The Obama administration is to announce Wednesday it will transfer leftover money from the largely successful fight against Ebola to combat the growing threat of the Zika virus, congressional officials say.

Roughly 75 percent of the $600 million or so would be devoted to the Centers for Disease Control, which is focused on research and development of anti-Zika vaccines, treating those infected with the virus and combating the mosquitoes that spread it. The rest would go to foreign aid accounts to fight the virus overseas.

The officials spoke on condition of anonymity because they were not authorized to publicly discuss the matter before the White House announcement.

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Foreign nationals from Ebola-affected countries can stay 6 more months

The Obama administration said Tuesday it will allow foreign nationals from Ebola-affected countries in West Africa to stay in the U.S. for another six months, even though global health officials said the outbreak that killed 11,000 people abroad is officially over.

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How Post-Ebola Syndrome is Making Life Difficult After the Dreaded Disease

submitted by Gavin Macgregor-Skinner

Al Jazeera America - (Tonight) Thursday, Jan 14, 2016 at 930pm EST 

Survivors of Ebola report strange symptoms as America Tonight examines how post-Ebola syndrome is making life difficult after the dreaded disease. (new, 30 minutes)

CLICK ON THE LINK BELOW - Watch at 930pm EST on Thursday, Jan 14, 2016
http://america.aljazeera.com/watch/shows/america-tonight.html

 

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Guinea’s Ebola Outbreak is Declared Officially Over

submitted by George Hurlburt / Mike Kraft

An MSF health worker holds baby Nubia Souma, the last known Ebola patient in Guinea.  Image: Samuel Aranda/MSF

CLICK HERE - WHO - STATEMENT - End of Ebola transmission in Guinea

(ALSO SEE SITUATION REPORTS AND RELATED ARTICLE BELOW)

Forty-two days have passed since the last person with Ebola tested negative for the virus.

thejournal.ie - by Sinead O'Carroll - December 29, 2015

THE WORLD HEALTH Organisation has declared the Ebola outbreak in Guinea officially over.

In a statement this morning, the global body confirmed that 42 days had passed since the last person with Ebola in the country tested negative for the virus for a second time.

Guinea will now enter a 90-day period of “heightened surveillance” to ensure any new cases are identified before being passed on to other people.

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(CLICK HERE - SEE RELATED ARTICLE)

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We’ve Learnt Many Lessons from This Outbreak and From the Response – Dr. David Nabarro, Special Envoy on Ebola

          

Dr. David Nabarro, Special Envoy on Ebola, at a press conference in New York in November 2015. UN Photo/Loey Felipe

un.org

10 December 2015 – In August 2014, amid a rapidly growing outbreak of Ebola, Dr. David Nabarro was tasked with providing strategic guidance for an enhanced international response, and galvanizing essential support for affected communities and countries. As the Secretary-General’s Special Envoy on Ebola, Dr. Nabarro played a key role in responding to the outbreak, which mainly affected Guinea, Liberia and Sierra Leone, and claimed more than 11,300 lives to date.

While the Ebola outbreak in West Africa has declined significantly in recent months, it is not completely over, making it all the more vital for everyone involved in the response to remain vigilant and focused on stopping the outbreak, staying at zero cases and preventing re-emergence. The Office of the Special Envoy will end its mandate on 31 December 2015, but the UN system will continue to remain fully engaged with the affected countries. 

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Another American Ebola Survivor Had Eye Problems

Ebola survivor Dr. Richard Sacra experienced eye problems, including vision loss, pain and redness, shortly after he recovered from the disease.

Credit: Chancellor JR, Padmanabhan SP, Greenough TC, Sacra R, Ellison RT III, Madoff LC, et al. Uveitis and systemic inflammatory markers in convalescent phase of Ebola virusdisease. Emerg Infect Dis. 2016 Feb

CLICK HERE - STUDY - CDC - Uveitis and Systemic Inflammatory Markers in Convalescent Phase of Ebola Virus Disease

livescience.com - by Rachael Rettner - November 25, 2015

Ebola survivor Dr. Ian Crozier wasn't the only American to experience eye problems following the disease — a new report describes eye problems in another American doctor who lived through the disease.

Dr. Richard Sacra, who works for the Christian mission organization SIM USA, contracted Ebola last year while caring for pregnant women in Liberia during the rise of the Ebola outbreak there. He was evacuated to the United States for treatment in early September 2014, and was declared Ebola-free after spending about a month in the hospital.

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