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Scientists to share real-time genetic data on deadly MERS, Ebola

REUTERS by Kate Kelland                     April 21, 2015

LONDON, April 21 - Genetic sequence data on two of the deadliest yet most poorly understood viruses are to be made available to researchers worldwide in real time as scientists seek to speed up understanding of Ebola and MERS infections.

The project, led by British scientists with West African and Saudi Arabian collaboration, hopes to encourage laboratories around the world to use the live data -- updated as new cases emerge -- to find new ways to diagnose and treat the killer diseases, and ideally, ultimately, prevent them.

"The collective expertise of the world's infectious disease experts is more powerful than any single lab, and the best way of tapping into this...is to make data freely available as soon as possible," said Jeremy Farrar, director of the Wellcome Trust global health charity which is funding the work.

The gene sequences, already available for MERS cases and soon to come in the case of Ebola, will be posted on the website virological.org for anyone to see, access and use.

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http://af.reuters.com/article/topNews/idAFKBN0NC19W20150421?sp=true

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Ebola rapid diagnostic kit developed by UK scientists in Sierra Leone

Doctors says the kit, if approved by health authorities, could transform the admissions process with its capacity to deliver results within 20 minutes

THE GUARDIAN    by Lisa O'Carroll                              March 29, 2015

A rapid Ebola diagnostic kit similar to a pregnancy kit has been developed by British military scientists and NHS medics in Sierra Leone.

Health care workers prepare to entering a high risk zone at an Ebola virus clinic in Sierra Leone, where the diagnostic kit has been undergoing tests. Photograph: Michael Duff/AP

It can be administered at the bedside and return its first results within 20 minutes, slashing dramatically the normal 24-hour turnaround for lab results.

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British Army medic with Ebola evacuated with two other suspected cases

THE TELEGRAPH  by  Victoria Ward and Ben Farmer   March 12, 2015  

A female Army medic who has caught Ebola while working in Sierra Leone is being flown back to Britain by the RAF, along with two workers who have been in close contact with her.

              Beatrice Yordoldo (Seated), an Ebola patient, poses for photographs with medical staff  Photo: AFP

Two further health workers who have been exposed to the unnamed soldier are being tested in Sierra Leone and could be evacuated later...

The woman is the third British health care worker confirmed to have caught the deadly virus...

Justine Greening, the Development Secretary, said the checks on the four other workers were "purely precautionary" after they had close contact with the female patient.

http://www.telegraph.co.uk/news/worldnews/ebola/11466376/British-Army-medic-with-Ebola-being-flown-back-to-UK.html

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UK Ebola medics under investigation

BBC                                                                      Feb.23, 2015

Five UK Ebola nurses and doctors are under investigation by regulators, Public Health England says.

They are looking into the screening of medics who flew back to England on 28 December after treating patients in Sierra Leone.

                  Pauline Cafferkey was diagnosed with Ebola in December after volunteering work in Sierra Leone

On this flight was Scottish nurse Pauline Cafferkey - who developed Ebola - and some of her colleagues.

Questions have arisen over the health assessments and protocols that were followed.

Media reports have suggested Ms Cafferkey may have had signs of Ebola before leaving Sierra Leone but regulators have not commented on this.

http://m.bbc.com/news/health-31586074

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Doctors Who Treat Ebola Feel More Socially Isolated

LIVESCIENCE.COM   by Rachael Rettner                                                                         Feb. 13, 2015

Doctors who take care of very sick Ebola patients may feel socially isolated, but surprisingly, they may not feel more stressed than usual, a new study from Germany suggests.

Researchers surveyed 46 health care workers who treated Germany's first Ebola patient in August 2014, as well as 40 health care workers who worked in the same hospital but did not treat the Ebola patient.

The researchers who did the study hypothesized that the people who treated the Ebola patient would have more symptoms of psychological distress because they were working in a challenging environment that presented a risk that they could become infected with the deadly virus.

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Ebola infection 'linked to visor'

THE PRESS ASSOCIATION                               Feb. 4, 2015
LONDON --A British nurse who contracted Ebola while working in Sierra Leone possibly caught the virus by wearing a visor and not goggles, an investigation has suggested.
Press Association - Save the Children said Pauline Cafferkey, pictured on her return to health, may have contracted Ebola by wearing a visor rather than goggles when treating patients in Sierra Leone

The report by Save the Children said it cannot be completely certain how Pauline Cafferkey contracted Ebola but said both pieces of equipment are "equally safe".

The nurse, from Cambuslang in South Lanarkshire, had volunteered with the charity at the Ebola Treatment Centre (ETC) in Kerry Town before returning to the UK in December....

Save the Children published the findings of an independent review into the possible causes of how the 39-year-old caught the virus. The report said both visors and goggles are safe but there are slight differences in the type of clothing worn with each and in the protocols for putting them on and removing them....

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Ebola tests for UK military worker

PRESS ASSOCIATION                                                                                                     Feb. 2, 2015

LONDON --A second UK military healthcare worker has been transported back to England after likely exposure to Ebola via a needle-stick injury while treating someone with the virus in Sierra Leone, Public Health England said.

 

               Press Association - The healthcare worker has been admitted to the Royal Free Hospital in London

The healthcare worker arrived in the UK today and has been admitted to the Royal Free Hospital in London where they are undergoing an assessment.

They have not been diagnosed with Ebola and do not have symptoms, Public Health England added.

It comes after another British military healthcare worker was flown back to England for monitoring after suffering a needle-stick injury, also in Sierra Leone.

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https://uk.news.yahoo.com/ebola-tests-uk-military-worker-105839068.html#tDyqh5N

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In pursuit of next-generation Ebola stockpile vaccines

REUTERS   by Kate Kell and Ben Herschler                                                                        Feb. 1. 2015
LONDON --As West Africa's devastating Ebola outbreak begins to dwindle, scientists are looking beyond the endgame at the kind of next-generation vaccines needed for a vital stockpile to hit another epidemic hard and fast.

 

Research assistant Georgina Bowyer works on a vaccine for Ebola at The Jenner Institute in Oxford, southern England January 16, 2015. Credit: Reuters/Eddie Keogh

Determined not to lose scientific momentum that could make the world's first effective Ebola interventions a reality, researchers say the shots, as well as being proven to work, must be cheap, easy to handle in Africa and able to hit multiple virus strains.

That may mean shifting focus from the stripped-down, fast-tracked vaccine development ideas that have dominated the past six months, but it mustn't mean the field gets bogged down in complexities.

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British Ebola patient recovering, no longer critical, says hospital

REUTERS                                                                                    Jan. 12, 2015

LONDON- A British nurse diagnosed with Ebola last month is recovering and is no longer in a critical condition, the London hospital treating her said in a statement on Monday.

Pauline Cafferkey, a 39-year-old nurse who normally works at a Scottish health center, became the first person to be diagnosed with the disease in Britain after contracting it in Sierra Leone where she was volunteering at an Ebola clinic.

"Pauline Cafferkey is showing signs of improvement and is no longer critically ill," the statement from the Royal Free Hospital said. "She remains in isolation as she receives specialist care for the Ebola virus."

Cafferkey is being treated with blood plasma from an Ebola survivor and an unnamed experimental anti-viral drug, the hospital has said.

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http://news.yahoo.com/british-ebola-patient-recovering-no-longer-critical-says-141357956.html;_ylt=AwrBEiLsF7RUKgYAww_QtDMD

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J&J, Bavarian Nordic start clinical tests in Ebola vaccine race

REUTERS     by Ben Hirschler                              Jan. 6, 2015
LONDON --Johnson & Johnson has started clinical trials of its experimental Ebola vaccine, which uses a booster from Denmark's Bavarian Nordic, making it the third such shot to enter human testing.

The initiation of the Phase I study in Britain, which had been expected about now, marks further progress in the race to develop a vaccine against a disease that has killed more than 8,000 people in West Africa since last year.

Two other experimental vaccines, one from GlaxoSmithKline and a rival from NewLink and Merck, are already in clinical development. However, the J&J vaccine offers a different approach, since it involves two separate injections.

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http://www.reuters.com/article/2015/01/06/us-health-ebola-vaccine-j-j-idUSKBN0KF0HH20150106

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