In October, scientists set out to do something unprecedented – conduct a drugs trial during an epidemic to find a treatment for a lethal disease. Could they make history and change the way we deal with outbreaks?
THE GUARDIAN by Sarah Boseley Feb, 17, 2015
In depth description of efforts by a group of Oxford University scientists to run field trials of drugs for use against Ebola.
" ...The little band of scientists had flown to Guinea on 16 October to do something that had never been successfully done before – set up a trial of experimental drugs against an infectious disease in the middle of an epidemic. Because the Ebola virus does not exist at low levels in any population, unless you run a properly conducted trial while the storm is raging, you will never have drugs that are proven to be effective. The Oxford team’s trial would not only aim to find a drug that worked against Ebola but also to establish a blueprint for the way drug trials would be run during outbreaks in the future. This did not just apply to fighting Ebola: if the scientists were successful, their trial would develop protocols for testing drugs for any epidemic, be it Sars or flu...."
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