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With Many Ebola Survivors Ailing, Doctors Evaluate Situation

ASSOCIATED PRESS  by Carley Petesch              Aug. 23, 2015

DAKAR, Senegal --Lingering health problems afflicting many of the roughly 13,000 Ebola survivors have galvanized global and local health officials to find out how widespread the ailments are, and how to remedy them.

The World Health Organization calls it an emergency within an emergency. Many of the survivors have vision and hearing issues. Some others experience physical and emotional pains, fatigue and other problems. The medical community is negotiating uncharted waters as it tries to measure the scale of this problem that comes on the tail end of the biggest Ebola outbreak in history.

"If we can find out this kind of information, hopefully we can help other Ebola survivors in the future," Dr. Zan Yeong, an eye specialist involved in a study of health problems in survivors in Liberia, told The Associated Press.

About 7,500 people will enroll — 1,500 Ebola survivors and 6,000 of their close contacts — and will be monitored over a five-year period in the study launched by Partnership for Research on Ebola Vaccines in Liberia, or PREVAIL.

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Cheap Paper Test to Screen Patients for Ebola, Yellow Fever, Dengue

MEDGADGET                                                                                   Aug. 20, 2015

BOSTON --At the 250th National Meeting & Exposition of the American Chemical Society this week, researchers from MIT, Harvard Med School, and the FDA are showing off a new field test that can quickly screen people for Ebola, yellow fever, and dengue. While the researchers don’t claim their technique to be as accurate as PCR and ELISA, it is nevertheless an excellent tool in poor areas of the world where these diseases tend to thrive.

The test doesn’t require any water or electricity nor any complicated and expensive equipment. It works similar to pregnancy tests, providing a color readout that signals whether a disease is detected that is easily readable by just about anyone.

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Ebola: What Happened

COUNCIL ON FOREIGN RELATIONS  BY John Campbell
(Scroll down for Laurie Garett's essay "Ebola's Lessons.")

With a rapidly growing and urbanizing population, persistent poverty, and weak governance, Sub-Saharan Africa is likely to be the source of new epidemics that potentially could spread around the world. Understanding the disastrous response of African governments, international institutions, and donor governments to the Ebola epidemic is essential if history is not to be repeated yet again. That makes Laurie Garrett’s essay, “Ebola’s Lessons,” in the September/October 2015 issue of Foreign Affairs, essential reading.

The Ebola virus treatment center where four people are currently being treated is seen in Paynesville, Liberia, July 16, 2015. (Courtesy Reuters/James Giahyue)

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Some Ebola Survivors Still Suffer—And Doctors Don’t Know Why

SCIENCE    by  Katie  M. Palmer                      Aug. 15, 2015

For the communities in Guinea, Sierra Leone, and Liberia where Ebola took the greatest toll last year, the worst is over. After claiming 11,000 lives, the fatal virus has finally begun to retreat. Numbers of new Ebola cases are dwindling. But for some of the survivors—the 50 percent or so of the infected who pull through—Ebola’s effects still linger.

                            Ebola survivor Fayiah, 11, sits with her relatives in Monrovia, Liberia. Jerome Delay/AP

For the communities in Guinea, Sierra Leone, and Liberia where Ebola took the greatest toll last year, the worst is over. After claiming 11,000 lives, the fatal virus has finally begun to retreat. Numbers of new Ebola cases are dwindling. But for some of the survivors—the 50 percent or so of the infected who pull through—Ebola’s effects still linger.

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Handwashing in W.African schools protects children, families from Ebola: UN

REUTERS by Monica MacSwan                                                                     Aug. 12, 2015

LONDON -- Handwashing and giving out soap in schools in Guinea, Liberia and Sierra Leone have helped to keep classrooms Ebola-free this year but schools need to remain vigilant after the summer holidays, the U.N. children's agency said on Wednesday.

UNICEF said there had been no reported cases of students or teachers contracting Ebola at a school this year in the three worst-hit countries in West Africa, where the virus has killed nearly 11,300 people since the outbreak began in late 2013.

In Liberia, where there have been as many as 4,800 deaths, two schools were decontaminated as a precaution after one student died in June and another became infected in July.

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How Will We Ensure the New Ebola Vaccine Reaches Those Most in Need?

HUFFINGTON POST  by Director of UNDP’s HIV, Health and Development Group, Bureau of Policy and Programme Support      Aug. 10, 2015                                                                 

 We have reasons to be optimistic about the news of a new tool in the fight against Ebola. As in the fight against HIV, science and solidarity have come together to save lives. The phase III trials on efficacy of the VSV-ZEBOV vaccine have yielded an impressive result in a relatively short time -- 100 percent effectiveness in those receiving the vaccine.

While scientists still need to figure out how long the protective effect of the vaccine lasts, and how effective it will be among the general population and with different strains of the virus, without a doubt this is an important tool for the protection of health and community workers and possibly the wider community. This will certainly help in the on-going efforts to achieve the target of zero new Ebola cases and in overall recovery efforts.

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Proposed Ebola biobank would strengthen African science

NATURE by Erika Check Hayden                                                                             Aug. 10, 2015
As West Africa’s Ebola outbreak winds down, an effort is under way to make the best use of the tens of thousands of patient samples collected by public-health agencies fighting the epidemic.  Samples from the Ebola epidemic in West Africa are held by public-health agencies in the region and abroad. Daniel Berehulak/NYT/Redux/Eyevine

On 6–7 August, the World Health Organization (WHO) convened a meeting in Freetown, Sierra Leone, to discuss how to establish a biobank for up to 100,000 samples of blood, semen, urine and breast milk from confirmed and suspected Ebola patients, as well as swabs taken from the bodies of people who died from the virus. Held by health agencies in both West Africa and the West, the samples could be valuable in understanding how the current Ebola crisis evolved, preparing for future outbreaks and developing public-health research capacity in a region that depends on outside experts.

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Ebola Survivors Face Lingering Pain, Fatigue and Depression

NEW YORK TIMES  by Denis Grady                               Aug. 8, 2015

The Ebola outbreak that started more than a year ago seems to be waning at last. But now, West Africa faces another difficulty: More than 13,000 people survived the virus, and many have lingering health problems, psychological troubles like depression and post-traumatic stress disorder, and worries about returning to work to feed themselves and what is left of their families.

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Physicians: Global Vaccine Development Fund Could Save Billions

PHARMACEUTICAL PROCESSING by  Princeton University, Woodrow Wilson School of Public and International Affairs   Aug. 6, 2015

Ebola is a preventable disease, and yet a safe and effective vaccine has not been deployed. As with many vaccines, financial barriers persist: pharmaceutical companies see high costs with limited market potential, and government support is lacking. But there may be a solution to this vaccine crisis with the ability to save at-risk populations, according to a perspective piece written by physicians based at Princeton University, University of Pennsylvania and the Wellcome Trust.

The article, published in the New England Journal of Medicine, proposes the creation of a $2 billion global vaccine-development fund - supported by governments, foundations and pharmaceutical companies - that would carry promising vaccines through development to deployment. With initial support, the global vaccine fund could help make vaccines available for emergency use.

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Only two Ebola cases reported in past week, but risks remain: WHO

REUTERS  by Stephanie Nebehay                           Aug. 4, 2015

Guinea and Sierra Leone each recorded a single cases of Ebola in the past week, putting a year-end goal of ending the deadly epidemic within reach, although risks remain, the World Health Organization (WHO) said on Tuesday.

Tight surveillance and tracing contacts of infected people remain crucial, WHO Assistant-Director Bruce Aylward said. They are especially challenging during the heavy rains in August.

In the previous week to July 26, the two countries had seven confirmed cases, which was the lowest in the past year up until then, according to the WHO.

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http://www.reuters.com/article/2015/08/04/us-health-ebola-who-idUSKCN0Q91JM20150804

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