You are here

Sierra Leone

Ebola Assay Card | Elisa-Based Diagnostic - Google Science Fair

submitted by Gavin Macgregor-Skinner

Temperature-Independent, Portable, and Rapid Field Detection of Ebola via a Silk-Derived Lateral-Flow System

googlesciencefair.com - 2015

I developed a “stable and stored at room temperature” Ebola Assay Card, applicable as an ELISA-based diagnostic for diseases such as HIV, Lyme and certain cancers, that will allow for water-activated, timed-release detection of Ebola antigens, with detection limits that are analogous to current sandwich ELISA techniques. Reagents become chemically “stabilized” when mixed into silk, which enables them to remain “chemically active” without refrigeration. This Ebola Assay Card will allow for shipment and storage without refrigeration, and provide detection of the Ebola viral antigens based on color change in as little as 30 minutes.

(CLICK HERE FOR ADDITIONAL INFORMATION)

 

General Topic Tags: 
Problem, Solution, SitRep, or ?: 

Feds to end Ebola screening for air travelers from Liberia

USA TODAY by Bart Jansen                           Sept. 19, 2015

WASHINGTON – Federal authorities will end mandatory Ebola screening Monday for travelers from Liberia to five U.S. airports, but will continue to scrutinize travelers from Sierra Leone and Guinea, federal officials announced Friday.

The Department of Homeland Security's Customs and Border Protection had provided extra screening for more than 30,000 travelers during the past year, after an outbreak of the often fatal disease in West Africa.....

Customs and Border Protection and the Centers for Disease Control and Prevention agreed to remove Liberia from the list of countries subject to enhanced visa and port-of-entry screening, effective Monday....

The U.S. will maintain extra screening for travelers from Sierra Leone and Guinea, which still see a handful of new cases each week, and for people who traveled through those countries during the previous three weeks.

Read complete story.
http://www.usatoday.com/story/news/2015/09/18/ebola-travel-airport-screening-liberia-sierra-leone-guinea-customs-border-protection/72398942/

Problem, Solution, SitRep, or ?: 

Quarantines return as Ebola makes comeback in Sierra Leone

REUTERS    Sept.14, 2015
FREETOWN — Health authorities quarantined hundreds of people in northern Sierra Leone on Monday after a 16-year-old girl died of Ebola in an apparent case of sexual transmission, the first confirmed death from the virus in the district for nearly six months.

Sierra Leone celebrated last month when it discharged the last remaining Ebola patient from its treatment centers. But since then a new spate of cases has erupted, leaving two dead and five people in treatment.

The teenage girl, Kadiatu Thullah, died on Sunday at the International Medical Corps Ebola treatment unit, authorities said.

Emmanuel Conteh, head of the Ebola Response Centre for the district of Bombali in northern Sierra Leone, said that some 690 people in the village of Robuya where Kadiatu lived would be isolated for three weeks....it.

Conteh said health workers were investigating how the teenager got infected, since she had not traveled outside the village in years. Initial suspicions are that she had sex with an Ebola survivor.

Read complete story.

http://www.reviewjournal.com/news/nation-and-world/quarantines-return-ebola-makes-comeback-sierra-leone

Country / Region Tags: 
General Topic Tags: 
Problem, Solution, SitRep, or ?: 

Offline: A pervasive failure to learn the lessons of Ebola

THE LANCET by Richard Horton                         Sept. 12, 2015

LONDON-- Post-Ebola reverie has given birth to a plethora of expert panels to consider what went wrong. The latest parade of global health specialists appointed to learn lessons gathered at the Wellcome Trust in London last week.
 Under the auspices of the US Institute of Medicine (IOM), a Commission to “deliberate and evaluate options to strengthen global, regional, and local systems to better prepare, detect, and respond to epidemic diseases” spent 2 days amassing evidence.

 There was no shortage of experience brought to bear on these important matters. Here were Margaret Chan, Jeremy Farrar, Ilona Kickbusch, David Heymann, Larry Gostin, Joy Phumaphi, Joanne Liu, and Peter Piot all wrestling with a seemingly intractable challenge. The statements offered to the Commission were arresting. But  the purpose of the meeting was not to talk. It was to identify the best system for an epidemic response....
Read complete article

http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2815%2900152-X/fulltext

Problem, Solution, SitRep, or ?: 

3 New Ebola Patients Found in Sierra Leone

VOICE OF AMERICAN by James Butty  Sept. 9, 2015
Three more people have tested positive for Ebola from the same village in Sierra Leone's northern Kambia district of the country where a 67-year-old woman died last week from the virus, Sierra Leone health officials said.

Chief medical officer Dr. Brima Kargbo told VOA Tuesday the three new patients came from among the 50 high-risk persons identified as close relatives of the deceased woman. 

Sierra Leone has had nearly 14,000 cases of Ebola and about 4,000 deaths since the outbreak began in 2014.  But Dr. Kargbo said the latest outbreak is containable because its origin is traceable....

Read complete story.
http://www.voanews.com/content/new-ebola-patients-found-in-sierra-leone/2953488.html

Country / Region Tags: 
General Topic Tags: 
Problem, Solution, SitRep, or ?: 

WHO To Vaccinate 200 Individuals Following Recent Sierra Leone Ebola Death

TECH TIMES by rina Maria Doctor     Sept. 3, 2015
The World Health Organization (WHO) is set to vaccinate about 200 people in Sierra Leone, who were believed to have been directly or indirectly exposed to a woman who succumbed to death due to the virus on Saturday, Aug. 29.

The 67-year-old woman, whose diagnostic test results came positive for Ebola, was a merchant from the Kambia District, which is close to the border of Guinea. She died five days after Sierra Leone has begun a countdown projected to last for 42 days before the country may be declared free from the deadly virus. Before her diagnosis, the last patient diagnosed with the disease was reported on Aug. 8....

WHO will immunize the people in the area of Tonko Limba who have had direct and indirect exposures to the deceased, says Margaret Harris, a spokesperson from WHO. This effort will also include people who have had close contacts with the said exposed individuals....

Country / Region Tags: 
General Topic Tags: 
Problem, Solution, SitRep, or ?: 

Survey Finds Many Physicians Overestimate Their Ability to Assess Patients’ Risk of Ebola

massgeneral.org - August 27, 2015

While most primary care physicians responding to a survey taken in late 2014 and early 2015 expressed confidence in their ability to identify potential cases of Ebola and communicate Ebola risks to their patients, only 50 to 70 percent of them gave answers that fit with CDC guidelines when asked how they would care for hypothetical patients who might have been exposed to Ebola. In addition, those who were least likely to encounter an Ebola patient – based on their location and characteristics of their patients – were most likely to choose overly intense management of patients actually at low risk.  The results of the survey, conducted by a team of Massachusetts General Hospital (MGH) investigators, have been published online in the Journal of General Internal Medicine.

(READ COMPLETE ARTICLE)

CLICK HERE - RESEARCH - Ebola Risk and Preparedness: A National Survey of Internists 

General Topic Tags: 
Problem, Solution, SitRep, or ?: 

CDC - HHS - Ebola Concept of Operations (ConOps) Planning Template

Source:Centers for Disease Control and Prevention (CDC) - Date Published:08/20/2015

Annotation:This 38-page document provides a standard format for creating an Ebola Concept of Operations (ConOps) plan at the state, territorial, or major metropolitan area government level. It provides information on measures local governments, agencies, and organizations can take to support the plan. The ConOps in the template describes strategic, high-level considerations for establishing a regional tiered system to safely and effectively manage persons under investigation (PUIs) or patients confirmed with Ebola.

(38 page .PDF document)
URL: http://www.cdc.gov/phpr/documents/ebola-concept-of-operations-planning-template-8-20-2015.pdf

Authors:Dugas, Robert; Lamoureux, Joe; Mangieri, William; et al.
Type:Guideline/Assessment Tool
ID:11129. From Disaster LitTM, a database of the U.S. National Library of Medicine.

http://disasterlit.nlm.nih.gov/record/11129

General Topic Tags: 
Problem, Solution, SitRep, or ?: 

Sierra Leone Quarantines 50 Following Latest Ebola Death

VOICE OF AMERICA by James Butty  Sept. 2, 2015

 Sierra Leone Tuesday quarantined 50 people in the northern district of Kambia, where a 76 year-old woman died over the weekend from Ebola. The country had just celebrated the release from the hospital of its last known Ebola patient.

Abdulai Bayraytay, national publicity and outreach coordinator in the office of Sierra Leone’s government spokesman, told VOA the good news so far is that no one else has shown symptoms of the virus.

But Bayraytay said the woman’s death re-emphasizes the government’s warning for Sierra Leoneans to be vigilant, not intransigent....

The woman who died was supposedly sick for 5 to 10 days without the authorities knowing of her situation. Still, Bayraytay said there is a remote possibility Sierra Leone may see new cases of Ebola

Read complete story.
http://www.voanews.com/content/sierra-leone-quarantines-50-following-latest-ebola-death/2941906.html

Country / Region Tags: 
General Topic Tags: 
Problem, Solution, SitRep, or ?: 

Scientists Discover New Use for an Old Therapy Inhibiting Deadly Pathogens Including Ebola and Anthrax

                                                     

CLICK HERE - RESEARCH - Identification of agents effective against multiple toxins and viruses by host-oriented cell targeting

prweb.com - by Cynthia Lujan - September 1, 2015

A new host-based therapy for Ebola, anthrax and other deadly infectious diseases has been discovered by researchers at the Keck Graduate Institute and its collaborators. The discovery has the potential to speed to market treatments for previously untreatable diseases.

The findings were published online on August 27 by Scientific Reports, an open access research journal from the publishers of Nature.

The lead authors of the story were Leoor Zilberminitz and William Leonardi, doctoral students in KGI laboratory of assistant professor Mikhail Martchenko. The researchers screened a library of 1,581 drugs previously approved by the FDA for in vitro protection of mammalian cells against Bacillus anthracis lethal toxin and diphtheria toxin, which normally kill 50-70% of unprotected cells. They then investigated the 1% most promising compounds that both provided the best protection against the two toxins and were not toxic to uninfected cells.

General Topic Tags: 
Problem, Solution, SitRep, or ?: 

Pages

Subscribe to Sierra Leone
howdy folks
Page loaded in 0.659 seconds.