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Beyond the Immediate Tragedy: Ebola’s Long-Term Implications

THE ATLANTIC COUNCIL    October 1, 2014

 By J. Peter Pham

....beyond the immediate tragedy, there are significant short, medium, and long-term impacts that we are not even beginning to address.

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Rains complicate delivery of Ebola supplies in West Africa

 

Mon Sep 29, 2014 

WASHINGTON - The rainy season in West Africa is compounding difficulties in getting supplies delivered and new treatment centers built as donors rush to isolate people infected with the deadly Ebola virus and stop its rapid spread, U.S. officials said.

Nancy Powell, newly appointed as the U.S. State Department's envoy to coordinate its Ebola response, said the top priority is to isolate as many people as quickly as possible. But that faces significant logistical hurdles.

"Infrastructure challenges in the rainy season is one of the biggest difficulties. And you add the rain and getting materials out of the capital and it is very difficult," Powell said in a news briefing last week.

The July to September rainy season is coming toward its end, but October is known for heavy thunderstorms that can drench the region and turn roads to mud.

Eric Talbert, executive director of Emergency USA which has opened a 22-bed Ebola treatment center in Goderich, outside the capital of Freetown in Sierra Leone, said the downpours complicate getting supplies along unpaved single track roads that are washed out by the heavy rains..

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Situation Report Overview by the Associated Press

 

Bulk of promised global aid has yet to materialize on the ground

 The Associated Press Posted: Sep 28,  Updated: Sep 28, 2014 1:10 PM ET

  Doctors are in short supply. So are beds for patients. Six months after the Ebola outbreak emerged for the first time in an unprepared West Africa and eventually became the worst-ever outbreak, the gap between what has been sent by other countries and private groups and what is needed is huge.

Even as countries try to marshal more resources, those needs threaten to become much greater, and possibly even insurmountable....

Beds are filling up as fast as clinics can be built. Ambulance sirens blare through standstill traffic. Often, there is nowhere to take the sick except to "holding centres" where they await a bed at an Ebola treatment facility.

The virus has killed almost 3,000 people and infected more than 6,200 in Liberia, Sierra Leone, Guinea, Nigeria and Senegal.

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Overview of U.S.Defense Department activities against Ebola, including testing vaccine candidate

By Cheryl Pellerin

DoD News, Defense Media Activity

WASHINGTON, Sept. 26, 2014 – The Defense Department has made critical contributions to the fight against the deadly Ebola outbreak in West Africa, and today Defense Secretary Chuck Hagel described additional ways the Pentagon is helping in the broader battle against infectious disease outbreaks of the future.

He spoke at a gathering of top government and military officials and infectious disease experts from 44 countries here to attend the Global Health Security Agenda, or GHSA, Summit hosted by President Barack Obama.

Hagel said ...the department also is accelerating the manufacture of potential treatments and starting clinical trials for a vaccine candidate and it has received approval to begin safety testing for one [Ebola] vaccine candidate that will be conducted at the Walter Reed Army Institute of Research.”

...The DoD Cooperative Threat Reduction Program is providing unique resources and expertise to enhance detection and surveillance, Hagel said, and all department assets will help civilian responders contain Ebola's spread and mitigate its economic, social and political fallout.

For fuller description of the Defense Department's activities to counter Ebola see link to the full article:

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Doctor in Liberia reports some success in treating Ebola with an HIV drug

The Washington Post Follow-up to the original CNN report        Oct. 2, 2014

Since the original CNN interview, Logan has been in contact with Dr. Fauci. "I can't say it's a good idea or bad idea," Fauci told The Post this week. "It's one of those things where you're in a situation where you have no therapy, so you look for things that might be available."

Fauci said National Institutes of Health researchers have tested lamivudine's reaction to Ebola in test tubes. There was no response; but Fauci said researchers will adjust some levels and try it again "to see if there's even slight activity against Ebola."

If there is, he said, NIH would consider going to the trial stage.

It makes sense to consider lamivudine as a potential Ebola treatment: It belongs to a group of drugs known as nucleoside analogs, which interfere with the replication processes of certain viruses, Fauci explained.

See Washington Post report

http://www.washingtonpost.com/news/to-your-health/wp/2014/10/02/a-liberian-doctor-is-using-hiv-drugs-to-treat-ebola-victims-the-nih-is-intrigued/

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Tourists advised to avoid Ebola zones of West Africa

NEW YORK TIMES      September 26, 2014

By

 .... The C.D.C. has issued a Watch Level 3 warning (“avoid nonessential travel”) for Guinea, Sierra Leone and Liberia, and a Level 2 warning (“practice enhanced precautions”) for Nigeria and the Democratic Republic of Congo.

Tourists should not visit these areas. The C.D.C. has recommended that foreign exchange, research and other education-related travel be postponed until further notice. Although the situation can change rapidly, there is now no risk of contracting Ebola in countries in West Africa without reported cases.

Anyone in the affected countries who gets a fever and symptoms like headache, muscle pain, vomiting, diarrhea, stomach pain or unexplained bleeding or bruising should avoid all contact with others and travel immediately by private transportation to a doctor’s office or hospital.

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PRESIDENT OBAMA CALLS ON MORE NATIONS TO HELP COMBAT EBOLA

REUTERS

NEW YORK/FREETOWN Thu Sep 25, 2014 8:04pm EDT

(Reuters) - President Barack Obamatoday  called on more nations to help fight the world's worst outbreak of the deadly Ebola virus, saying hundreds of thousands of lives were at stake.

The warning came shortly after the World Health Organisation gave a rare hint of optimism in the West African crisis, announcing that the spread of the disease in Guinea appeared to have stabilised.

"More nations need to contribute critical assets and capabilities -- whether it's air transport, medical evacuation, health care workers, equipment or treatment," Obama told a meeting on Ebola on the sidelines of the U.N. General Assembly.

"If unchecked, this epidemic could kill hundreds of thousands of people in the coming months."

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U.S. Hospitals Unprepared to Handle Ebola waste, Experts Say

      

As Emory was treating two US missionaries who were evacuated from West Africa in August, their waste hauler, Stericycle, initially refused to handle it. Photograph: Michael Duff/AP

REUTERS      September 24, 2014

CHICAGO (Reuters) - U.S. hospitals may be unprepared to safely dispose of the infectious waste generated by any Ebola virus disease patient to arrive unannounced in the country, potentially putting the wider community at risk, biosafety experts said.

Waste management companies are refusing to haul away the soiled sheets and virus-spattered protective gear associated with treating the disease, citing federal guidelines that require Ebola-related waste to be handled in special packaging by people with hazardous materials training, infectious disease and biosafety experts told Reuters.

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Dr. Gavin Macgregor-Skinner, an expert on public health preparedness at Pennsylvania State University, said there's "no way in the world" that U.S. hospitals are ready to treat patients with highly infectious diseases like Ebola.

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London Group Plans to Start First Clinical Tests of Ebola Drugs in West Africa

Washington Post

by Abby Ohlheiser September 23 at 11:45 AM

London based scientists, working with international aid groups, are planning to start the first clinical trials in West Africa for drugs to treat Eboa. The trials could begin in a matter of months.

Wellcome Trust's $5 million initiative will include drugs from Mapp Biopharmaceutical, Sarepta and Tekmira, according to Reuters. Mapp makes zMapp, the experimental cocktail administered to two Americans who contracted the disease in Liberia. Tekmira recently gained the approval of the U.S. Food and Drug Administration to use its TKM-Ebola treatment on confirmed or suspected cases of the disease.

Both drugs are still in the experimental phase; researchers have not yet determined the safety or effectiveness of the treatments.

Text of full story:

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