Covid-19 treatment Paxlovid can interact with common heart medications, doctors warn | CNN Covid-19 patients with a history of cardiovascular disease are at an increased risk of developing severe illness and could benefit most from the Covid-19 treatment Paxlovid -- but there's a catch. Jacqueline Howard CNN

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Paxlovid can have dangerous interactions with some of the most common medications for cardiovascular disease, including certain statins and heart failure therapies, a new paper warns.

Novavax says COVID booster dose shows benefit against Omicron variants Novavax Inc said on Wednesday data from studies in adults and adolescents showed that the booster dose of its COVID vaccine produced robust antibodies against several Omicron variants, including BA.1, BA.2 and BA.5. Reuters Reuters

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FDA clears updated COVID boosters for kids as young as 5 The U.S. on Wednesday authorized updated COVID-19 boosters for children as young as 5, seeking to expand protection ahead of an expected winter wave. Tweaked boosters rolled out for Americans 12 and older last month, doses modified to target today’s most common and contagious omicron relative . AP NEWS

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There’s one more step before parents can bring their kids in for the new shot: The Centers for Disease Control and Prevention, which recommends how vaccines are used, must sign off.

Seattle to end COVID-19 emergency proclamation SEATTLE (AP) — The City of Seattle will end its COVID-19 emergency proclamation at the end of October. Mayor Bruce Harrell said in a statement Tuesday that Seattle will lift its remaining COVID emergency order to align with Gov. AP NEWS

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Myocarditis, pericarditis remains rare after COVID-19 booster Myocarditis and pericarditis after COVID-19 vaccination is rare across demographic groups and most likely to occur in teen boys in the week after their second shot of a two-dose vaccine, according to a study.

Myocarditis and pericarditis after COVID-19 vaccination is rare across demographic groups and most likely to occur in teen boys in the week after their second shot of a two-dose vaccine, according to a study.

'Africa on its own': Little help in epidemics, says official KAMPALA, Uganda (AP) — Africa must plan to respond effectively to disease outbreaks without international help, a top public health official said Wednesday, warning that the continent of 1.3 billion people is “on its own” during pandemics. AP NEWS

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Opinion | Covid is making us ungovernable Pandemics fuel pre-existing prejudices, deepen social divisions and increase political tensions. NBC News

By Brian Michael Jenkins, senior adviser to the president of RAND

AstraZeneca's COVID vaccine suffers a setback in nasal spray trial Attempts by Oxford University researchers and AstraZeneca Plc to create a nasal-spray version of their jointly developed COVID-19 shot suffered a setback on Tuesday as initial testing on humans did not yield the desired protection. Reuters Reuters

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Medium COVID Could Be the Most Dangerous COVID After you’re infected, the first few months may pose the greatest risks. Benjamin Mazer The Atlantic

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Monkeypox: A dangerous variant circulating in the DRC could go global | New Scientist There have been 120 suspected deaths from monkeypox in the Democratic Republic of the Congo this year, and the virulent Clade I virus may be to blame. There are fears it could follow the milder Clade II and go global #author.fullName} New Scientist

ALSO SEE: Outbreak Brief 11: Monkeypox in Africa Union Member States