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Surge of Ebola in Liberia May Be Linked to a Survivor

NEW YORK TIMES  by Sheri Fink                   July 10, 2015

A resurgence of Ebola in the last week in Liberia, which had been declared free of the disease, may have originated with a survivor still carrying the virus, according to scientists who analyzed the genetic sequence of the virus from the body of a 17-year-old Liberian boy who died of Ebola last week.

The boy’s virus did not match strains still circulating in the continuing outbreak in Guinea and Sierra Leone, meaning he was unlikely to have caught the virus through cross-border travel.

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Ebola Survivors May Be the Key to Treatment - For Almost Any Disease

submitted by George Hurlburt

      

A group of volunteer medical workers carry the bodies of Ebola victims to a car in order to bury them in Kptema graveyard in Kenema, Sierra Leone, on August 24, 2014. Mohammed Elshamy/Anadolu Agency/Getty Images

wired.com - by Erica Check Hayden - June 30, 2015

. . . The patients held the answer. If they survived, they carried antibodies that targeted the very viruses that had almost killed them. The samples he’d been working with didn’t contain antibodies, but if he could get blood from survivors, he might be able to figure out how to make the same antibodies that their immune systems had produced. It would not be easy or fast, but he couldn’t stand by while more people lost their lives—if not in this outbreak, then in the next one, or the next one after that. It was time for a new plan. . . .

. . . Once your body knows how to make antibodies specific to a disease, it never forgets . . . So physicians use survivor serum in the hope that amid the trillions of antibodies an adult human can make, the ones that fight a specific disease will be in the mix. It’s not a new idea.

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Study of Ebola Survivors Opens in Liberia

Trial to examine long-term health effects of Ebola virus disease

nih.gov - June 17, 2015

The Liberia-U.S. clinical research partnership known as PREVAIL has launched a study of people in Liberia who have survived Ebola virus disease (EVD) within the past two years. The study investigators hope to better understand the long-term health consequences of EVD, determine if survivors develop immunity that will protect them from future Ebola infection, and assess whether previously EVD-infected individuals can transmit infection to close contacts and sexual partners. The study, sponsored by the Ministry of Health of Liberia and the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, will take place at various sites in Liberia and is expected to enroll approximately 7,500 people, including 1,500 people of any age who survived EVD and 6,000 of their close contacts.

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Finger-prick, blood test for Ebola takes just minutes

THE WASHINGTON POST by

Public health officials may soon be able to screen patients for Ebola at border crossings and hospitals with a finger-prick blood test that takes mere minutes.

The development of the rapid diagnostic test, reported in The Lancet Thursday, represents a significant victory for scientists around the world who have been experimenting over the past year with all manner of vaccines, treatments and other ways of eradicating the virus.

Developing a way of confirming Ebola in a patient has been one of the top priorities. In the early stages the symptoms -- chest pain, cough, nausea -- can look like many other illnesses, making it very difficult for doctors to triage -- to determine who should be quarantined and who to send home. It can often take days or longer for laboratory tests, the current standard, to return a positive or negative result.

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Neglected Tropical Diseases in the Ebola- Affected Countries of West Africa

PLOS   EDITORIAL by Peter J. Hotez, Sabin Vaccine Institute                          June 25, 2015
While global attention in West Africa is focused on the emergence of Ebola virus infection, new information from the published literature and World Health Organization databases reveals that many other neglected tropical diseases (NTDs) are far more widespread and also require urgent attention.
Well before Ebola virus infection emerged in West Africa at the end of 2013, the three
major affected countries--Guinea, Liberia, and Sierra Leone were already known to
be highly affected by NTDs....
Today, new information from the recent literature and the World Health Organization
(WHO) Preventive Chemotherapy and Transmission (PCT) Control databases reveals that
NTDs remain widespread in Guinea, Liberia, and Sierra Leone.  An estimated
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Malaria morbidity and mortality in Ebola-affected countries caused by decreased health-care capacity, and the potential effect of mitigation strategies: a modelling analysis

LANCET by Patrick G. T. Walker and others                               Volume 15, No. 7, p825–832, July 2015
The ongoing Ebola epidemic in parts of west Africa largely overwhelmed health-care systems in 2014, making adequate care for malaria impossible and threatening the gains in malaria control achieved over the past decade. We quantified this additional indirect burden of Ebola virus disease.

We estimated the number of cases and deaths from malaria in Guinea, Liberia, and Sierra Leone from Demographic and Health Surveys data for malaria prevalence and coverage of malaria interventions before the Ebola outbreak. We then removed the effect of treatment and hospital care to estimate additional cases and deaths from malaria caused by reduced health-care capacity and potential disruption of delivery of insecticide-treated bednets. We modelled the potential effect of emergency mass drug administration in affected areas on malaria cases and health-care demand....

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Liberia: Two-Hour School in Lofa County - Students in Class 8-10am

ALLAFRICA  by Mae Azango                                                                   June 10, 2015

Children in Gorlu, Salayea District Lofa County, are only in school two hours a day, or not in school at all. The reason? Their teachers are either running behind their salaries, or volunteer teachers are trying to get their names on the government's payroll.

Matthew Gahndolo, the school's principal laments, "The government of Liberia says, free and compulsory primary education, but what is the use when the children come to school by 8:00 a.m. and leave the class room after 10:00 a.m. to go on the farms, because their teachers are running behind salaries"

The situation of teachers leaving the classrooms and running behind salaries, and lack of qualified teachers to teach the children in rural Liberia, is not only restricted to Lofa County, but nearly all of the fifteen counties in Liberia. With the situation becoming increasingly alarming and dreadful, the government has also witnessed aggrieved health workers also on the streets demanding the Ebola risk benefits as well.

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http://allafrica.com/stories/201506100717.html

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Liberians still face travel headaches, stigma abroad even after country declared Ebola-free

ASSOCIATED PRESS By KRISTA LARSON                   June 19, 2015

DAKAR  Senegal  — Robtel Neajai Pailey hadn't been back home to Liberia since Ebola engulfed the country's capital in July, fearful that doing so could make it harder for her to travel as countries around the globe clamped down on visitors with West African passports.

So it was a mix of shock and anger earlier this month when she couldn't get a visa to attend an important meeting in the United Arab Emirates that had been months in the making.

It didn't matter that she had not even been in Liberia during the epidemic. Nor did it matter that Liberia was declared Ebola-free more than a month ago.

"It's not just affecting people who are in the country — it's all of us who have Liberian passports," said Pailey, an academic, activist and author who is based at SOAS, University of London.

The World Health Organization declared Liberia Ebola-free in early May. Still, fear of the deadly disease still reigns in many places, causing students to miss out on scholarships abroad, and keeping relatives from attending weddings and funerals.
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Staying at zero: Keeping Ebola out of Liberia


WHO                                                                  June 19, 2105
Ebola transmission may be over in Liberia, but in northwestern Lofa County health officials are concerned about its return. The virus first surfaced in the county in March 2014 via a traveller from Guinea and went on to devastate the country.

All 6 districts of northwestern Lofa County share a border with Guinea or Sierra Leone, where the Ebola transmission continues. Every day, hundreds of people pour into Lofa from the 2 Ebola-hit countries — traders, merchants, farmers and other economic migrants, relatives of Liberians attending weddings and funerals and patients going to Liberian health centres in border towns. On market days, the numbers double. They enter Liberia through 33 official border checkpoints and nearly 300 unofficial, mostly unmanned crossings.

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Ebola showed aid delivery desperately needs an overhaul

REUTERS  by Stella Dawson                                                          JUNE 18, 2015

WASHINGTON -- The Ebola epidemic exposed long-standing holes in aid delivery,  which desperately needs an overhaul before the next international emergency hits, aid experts said on Thursday.

Supplies for the Ebola zone in West Africa wait to be loaded at New York's John F. Kennedy International Airport September 20, 2014. REUTERS/Carlo Allegri

Many of the shortcomings seen during the Haiti earthquake of slow responses and uncoordinated relief efforts were repeated during the Ebola crisis that erupted in West Africa a year ago, they said.

With Sierra Leone and Guinea continuing to report cases of the deadly virus, the international community must act urgently, said Carolyn Reynolds, external relations manager at the World Bank.

"We need to think outside the box," she said at a panel on global health preparedness held on Capitol Hill.

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www.trust.org/item/20150618215202-ilvea/?source=fiOtherNews2

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