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Scientists ask if Ebola immunizes as well as kills

LONDON/DAKAR--A recent sharp drop in new Ebola infections in West Africa is prompting scientists to wonder whether the virus may be silently immunizing some people at the same time as brutally killing their neighbors.

A health worker disinfects a road in the Paynesville neighborhood of Monrovia, Liberia, January 21, 2015. Credit: Reuters/James Giahyue

So-called "asymptomatic" Ebola cases - in which someone is exposed to the virus, develops antibodies, but doesn't get sick or suffer symptoms - are hotly disputed among scientists, with some saying their existence is little more than a pipe dream.

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After Ebola: Why Rural Development Matters in a Time of Crisis

COMMENTARY:  HUFFINGTON POST  by President, International Fund for Agricultural Development (IFAD)                                                                                                                                 Jan. 26, 2015

....Now we must begin to look at what happens to the affected communities after Ebola. A food crisis seems increasingly likely to follow in the wake of the epidemic, which has devastated small-scale farmers. Without investment in their long-term development, farming households - and West Africa's future food security - will remain at risk.

Even before the outbreak, the World Food Programme estimated that some 1.7 million people in the region faced food insecurity - defined as a lack of reliable access to sufficient quantities of affordable, nutritious food. As a direct result of Ebola, it is expected that an additional 750,000 to 1.4 million people will become food-insecure by March.

In fact, Ebola has already affected the food supply. Farmers have stayed away from their fields due to illness, fears of infection and quarantines ordered by the authorities - or simply because there is no one left to tend the land....

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Studies detail Ebola spread, response steps

Four new studies shed new light on Ebola transmission and countermeasures.

CENTER FOR EFFECTIVE FOR RESEARCH AND POLICY  by Lisa Schnirring                                        Jan. 23, 2015

French and Guinean researchers  noted how chains of transmission helped Ebola spread in Conakry, Guinea, the first of the region's capital cities to be hit by the virus, and US officials released three detailed reports on outbreak response.

The Conakry team looked at seven transmission chains that occurred in the area from March to August 2014. They reported their findings in The Lancet Infectious Diseases.

In the first of three reports Friday in Morbidity and Mortality Weekly Report (MMWR), extra flight contact tracing measures undertaken after a Texas nurse took two flights shortly before getting sick with Ebola in October identified 268 people from nine states, none of whom got sick with the virus

In the second report, CDC estimates on the impact of Ebola treatment units (ETUs) and community care centers (CCCs) in Liberia predict that the interventions prevented thousands of new infections and that the interventions when used together were likely had a bigger impact than either alone.

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Ebola: Decline encouraging, but critical gaps remain

 

MEDECINS SANS FRONTIERES                                                                         Jan. 26, 2015

A downward trend of new cases is reported in Médecins Sans Frontières (MSF) Ebola management centres across Guinea, Liberia and Sierra Leone, with just over 50 patients currently in its eight centres. While this is a promising development, the medical-humanitarian organisation cautions that loss of vigilance now would jeopardise the progress made in stemming the epidemic.

“This decline is an opportunity to focus efforts on addressing the serious weaknesses that remain in the response,” says Brice de la Vingne, MSF Director of Operations.  “We are on the right track, but reaching zero cases will be difficult unless significant improvements are made in alerting new cases and tracing those who have been in contact with them.”

The World Health Organization reported last week that only about half of new cases in both Guinea and Liberia are from known Ebola contacts, while in Sierra Leone there is no data available.  “A single new case is enough to reignite an outbreak,” continues de la Vingne. “Until everyone who has come into contact with Ebola has been identified, we cannot rest easy.”

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Report by the Director-General to the Special Session of the Executive Board on Ebola

 

Statement by Dr. Margaret, Director-General of the World Health Organization to a Special Session of the Executive Board on Ebola

WHO PRESS OFFICE, Geneva                                                                                       Jan. 25, 2015

Excerpt:

"The Ebola outbreak points to the need for urgent change in three main areas: to rebuild and strengthen national and international emergency preparedness and response, to address the way new medical products are brought to market, and to strengthen the way WHO operates during emergencies."

Read complete statement.

http://www.who.int/dg/speeches/2015/executive-board-ebola/en/

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WHO Board Agrees on Reforms to Fix Ebola Response Mistakes

GENEVA-- The World Health Organization’s board agreed to create a special fund to respond to such outbreaks as Ebola and to set up a global health emergency workforce after the organization acknowledged mis-steps in its response to the epidemic.

 The WHO’s executive board agreed “in principle” at a meeting in Geneva Sunday to a contingency fund, and asked Director General Margaret Chan to develop by May options on its size and sources. Chan should also take immediate steps to establish a public-health reserve workforce that can be promptly deployed in response to health emergencies, according to the resolution adopted by senior health officials from 34 countries.

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Sierra Leone eases blocks on travel, business as Ebola wanes

ASSOCIATED PRESS  by Clarence Roy-Macaulay                                                                  Jan. 23, 2015

FREETOWN, Sierra Leone (AP) -- With the Ebola outbreak weakening in West Africa, Sierra Leone eased restrictions on movement and commercial activity Friday even as the president warned that the fight against the deadly disease is not yet over.

The outbreak has sickened more than 21,000 people, nearly half of them in Sierra Leone. But the number of new infections is now falling in Sierra Leone, Guinea and Liberia, the three most affected countries.

President Ernest Bai Koroma announced in a national broadcast that, starting Friday, the country would lift all district quarantines and extend business hours on Saturdays. Koroma said that while people must remain vigilant, easing the restrictions would jump-start the economic recovery. In addition to its human toll, Ebola has hammered the economies of the three most affected West African nations...Sierra Leone plans to reopen schools in March...

Read complete story.
http://news.yahoo.com/sierra-leone-eases-blocks-travel-160805983.html;_ylt=AwrBEiI3ssNUX2IAGH3QtDMD

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Ebola Infections Dropping in West Africa, World Health Organization Says

NEW YORK TIMES by NICK CUMMING-BRUCE                                                                         Jan. 23, 2015

GENEVA — The number of people falling victim to the Ebola virus in West Africa has fallen to the lowest level in months, the World Health Organization said on Friday, but dwindling funds and a looming rainy season threaten to hamper efforts to control the disease.

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As Ebola Outbreak Recedes, Global Health Care Leaders Focus On Prevention, Coordinated Action

THE INTERNATIONAL BUSINESS TIMES   by Amy Nordrum                                                                      Jan. 23, 2015

The recent Ebola outbreak, for which the number of new cases reported each week in the three most severely affected countries is finally beginning to fall, underscores the need to prepare for the next disease outbreak. Global health leaders are asking what it will take to prevent the next disease outbreak from spiraling out of control as the global population approaches 7.5 billion people and grows more connected.

 

     A research assistant works on a vaccine for Ebola at the Jenner Institute in Oxford, England. Eddie Keogh/Reuters

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WHO says cash crunch, rains could thwart Ebola efforts

REUTERS             by Stehane Nebehy                                                                                    Jan. 23, 2015

GENEVA --Halting the spread of Ebola in West Africa will depend on mobilising funds and aid workers before the rainy season hits in April-May, otherwise it could up to take a year, the World Health Organization (WHO) warned on Friday.

But the WHO is set to run out of cash in mid-February, a key period as it tries to halt the deadly disease, a senior WHO official said.

"It is a programme that can stop transmission if we have the money and the people, and we don't have either," Dr. Bruce Aylward, WHO assistant director-general in charge of the Ebola response, told a news briefing before a special session of WHO's Executive Board on Sunday.

Read complete report.
http://www.reuters.com/article/2015/01/23/us-health-ebola-who-idUSKBN0KW1NL20150123

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