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Ebola could cost West Africa $15 billion over three years

REUTERS  by Misha Hussain                                                    March 12, 2015sC

(Scroll down for links to press release and full report.)

DAKAR -- West Africa may lose up to $15 billion over the next three years due to the impact of the Ebola outbreak on trade, investment and tourism, according to a report by the United Nations.

The world's deadliest Ebola epidemic has killed almost 10,000 people in the three most affected countries of Guinea, Liberia and Sierra Leone, deepening poverty in one of the least developed parts of the world.

"The consequences of Ebola are vast," said Abdoulaye Mar Dieye, Africa director of the United Nations Development Programme (UNDP).

"Stigma and risk aversion have caused considerable amounts of damage, shutting down borders and indirectly affecting the economies of a large number of countries in the sub-region."

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http://news.yahoo.com/ebola-could-cost-west-africa-15-billion-over-150805196.html;_ylt=AwrBJSCTtwFVoAIAda3QtDMD

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Study Indicates Ebola-Infected Sewage May Require Longer Holding Period

INFECTION CONTROL TODAY                                          March 11, 2015
Storing Ebola-infected sewage for a week at 86 degrees Fahrenheit or higher should allow enough time for more than 99.99 percent of the virus to die, though lower ambient temperatures may require a longer holding period, according to a new study by researchers at Georgia State University's School of Public Health.

The study co-authored by Lisa M. Casanova, assistant professor of environmental health, and Scott R. Weaver, research assistant professor in Epidemiology and Biostatistics, used bacteriophage Φ6, a type of virus, as a stand-in to study how long Ebola and similar viruses can survive in latrines and other systems for collecting and disposing of sewage. Bacteriophage Φ6 has a lipid envelope, meaning it has structural similarities to Ebola and several other types of virus, allowing for a safe study that did not require use of Ebola itself.

"The places hardest hit by Ebola are the places that often have the least infrastructure for safely disposing of sewage and are using things like pit latrines," says Casanova. "They need the answers to questions like this."

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No new Ebola cases in Liberia for more than two weeks: WHO

AFP                                                                                                                       March 11, 2015

Geneva  - No new case of the deadly Ebola virus has been registered in Liberia since February 19, the World Health Organization said Wednesday, also hailing positive signs in Sierra Leone and Guinea.

                      A man walks past an Ebola campaign banner with the new slogan "Ebola Must GO" in Monrovia

Liberia, long the hardest-hit country in the Ebola epidemic that has killed nearly 10,000 people in west Africa, "has now gone well over two weeks without a new reported case," said Bruce Aylward, who heads WHO's Ebola response....

The outlook was less positive in the other countries affected by the outbreak, Guinea and Sierra Leone, although Aylward highlighted positive signs there too.
Read complete story.
http://news.yahoo.com/no-ebola-cases-liberia-more-two-weeks-175855158.html;_ylt=AwrBJR9j5gBVAQYArDLQtDMD

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Waning interest is biggest risk in race to overcome Ebola: WHO

REUTERS     by Tom Miles                                                                                        March 11, 2015

GENEVA -Waning interest in Ebola could jeopardize efforts to stamp out the world's worst recorded outbreak of the disease, the World Health Organization said on Wednesday.

Nameplates are seen at a cemetery for victims of Ebola virus in Suakoko, Liberia, March 11, 2015.  Reuters/James Giahyue

Case numbers have fallen to a low level and it should be possible to stop transmission by mid-year, but the disease is "not waning" and it is much too early to assume the outbreak will end, said WHO Assistant Director General Bruce Aylward.

"We talk often about how steep the drop in cases has been. The only thing that has dropped more quickly and more steeply is the new contributions in financing," he told reporters in Geneva. 

...the failure to make further inroads is "alarming", Aylward said.

"Getting from here to zero is going to require another reinvestment (in the drive to tackle the outbreak)."

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Why we’re still waiting on an Ebola vaccine

Researchers are scrambling to start trials before the outbreak fades, but establishing faith in vaccines will take time

AL JAZEERA AMERICA  by

FREETOWN, Sierra Leone — Since Ebola hit this coastal city last summer, nurses at Connaught Hospital have put their lives on the line by working with patients at risk of the deadly disease. Now researchers aim to recruit them as well as ambulance drivers and other hospital staff as subjects in one of the largest Ebola vaccine trials to date.

But just a few weeks before the trial begins enrollment, many health care workers are voicing discomfort about the shot. “It would be really good to have a vaccine, but we’re scared because it’s new,” said Kadiatu Nubieu, a nurse at Connaught.

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A panel of independent experts to assess WHO's response in the Ebola outbreak

WHO PRESS RELEASE                                                March 10, 2015

The WHO Director-General has commissioned a panel of outside independent experts to undertake an assessment on all aspects of WHO’s response in the Ebola outbreak. This is in response to a resolution passed during the Ebola Special Session of the Executive Board in January 2015.

Dame Barbara Stocking will chair the panel. She was formerly Chief Executive of Oxfam GB (2001-13) and during this time led major humanitarian responses. Currently she is President of Murray Edwards College, University of Cambridge, UK.

The other panel members are: Professor Jean-Jacques Muyembe-Tamfun, Director-General of the National Institute for Biomedical Research, Democratic Republic of the Congo; Dr Faisal Shuaib, Head of the National Ebola Emergency Operations Center, Nigeria; Dr Carmencita Alberto-Banatin, independent consultant and advisor on health emergencies and disasters, Philippines; Professor Julio Frenk, Dean of the Faculty, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA; and Professor Ilona Kickbusch, Director of the Global Health Programme at the Graduate Institute of International and Development Studies, Geneva, Switzerland.

The panel will present a first progress report on its work to the 68th World Health Assembly in May 2015.

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Economist: Some high-tech solutions fail with fight against Ebola in West Africa

THE ECONOMIST                                                                                                   March 9, 2015

As in all Ebola episodes, preventing infection in West Africa during what has been the worst outbreak in history has placed a lot of effort on looking after those dealing with the victims. New high-tech equipment is now available for use by health care workers, but in some countries it may be inappropriate....

Health care workers inside a USAID-funded Ebola clinic in Liberia wearing protective gear. Some of the best protective gear or technology is not available to African countries because of high costs or other conditions.  Photos by Abbas Dulleh • Associated Press,

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First look at hospitalized Ebola survivors' immune cells could guide vaccine design

MEDICALXPRESS                                                                                                 March 9, 2015
Researchers from Emory and the Centers for Disease Control and Prevention have now obtained a first look at the responses in four Ebola disease survivors who received care at Emory University Hospital in 2014, by closely examining their T and B cells during the acute phase of the disease. The findings reveal surprisingly high levels of , and have implications for the current effort to develop vaccines against Ebola.

The Ebola virus, isolated in November 2014 from patient blood samples obtained in Mali. The virus was isolated on Vero cells in a BSL-4 suite at Rocky Mountain Laboratories. Credit: NIAID

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Postmortem Stability of Ebola Virus

A CDC study suggests that the Ebola virus may still be able to cause disease a week after a person infected with the virus has died.

CDC  EMERGING INFECTIOUSNESS DISEASE JOURNAL        March, 2015
Abstract

The ongoing Ebola virus outbreak in West Africa has highlighted questions regarding stability of the virus and detection of RNA from corpses. We used Ebola virus–infected macaques to model humans who died of Ebola virus disease. Viable virus was isolated 7 days posteuthanasia; viral RNA was detectable for 10 weeks.

Read complete study.

http://wwwnc.cdc.gov/eid/article/21/5/15-0041_article

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How big data is beating Ebola

Computational epidemiologists at Virginia Bioinformatics Institute (VBI) have been working to combat the world’s largest and deadliest outbreak of Ebola. - See more at: http://www.information-age.com/technology/information-management/123459120/how-big-data-beating-ebola#sthash.CTk2zlgo.dpuf
Computational epidemiologists at Virginia Bioinformatics Institute (VBI) have been working to combat the world’s largest and deadliest outbreak of Ebola. VBI’s Bryan Lewis writes - See more at: http://www.information-age.com/technology/information-management/123459120/how-big-data-beating-ebola#sthash.CTk2zlgo.dpuf
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