Situation Report

Ebola death toll passes 10,000: WHO

AFP                                                                                                                    March 12, 2015
(Scroll down for WHO report.)

Geneva -- The global death toll from the Ebola outbreak centred in west Africa has topped 10,000 out of more than 24,000 recorded cases, the World Health Organization said Thursday.

Almost all the deaths and cases have been reported in the three west African countries worst hit by the outbreak: Sierra Leone, Liberia and Guinea.

Sierra Leone, which has overtaken Liberia as the country with the most infections, counted 11,677 cases and 3,655 deaths as of March 10.

As of March 5, Liberia -- long the hardest-hit country -- had recorded a total of 9,343 and 4,162 deaths.

But the tide seems to be turning in the country which in August and September was reporting more than 300 new cases each week, with the WHO saying Wednesday that Liberia had registered no new cases since February 19.

In Guinea, where the outbreak started in December 2013, 3,330 Ebola cases and 2,187 deaths were recorded as of March 10.

The WHO said on Wednesday that the country had seen no new cases in the previous 10 days.

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UNMC dean who just returned from Sierra Leone, another Ebola expert agree: Fight not over

OMAHA WORLD-HERALD by  Bob Glissman                                                             March 11, 2015

  The West African countries hit hardest by the Ebola virus and the countries and groups that have helped battle the disease must remain vigilant if the number of new Ebola cases is to get to zero, health experts said Wednesday.
Dr. Ali Khan, dean of the University of Nebraska Medical Center’s College of Public Health, spent a month in Sierra Leone as a consultant on Ebola for the World Health Organization. 

Dr. Ali Khan, who returned to Omaha late last week after a month in Sierra Leone, said progress is evident, but he cautioned officials there against becoming complacent. “Because with a disease like Ebola,” he said, “all you need is one case to restart an outbreak or a cluster of cases.”

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Ebola could cost West Africa $15 billion over three years

REUTERS  by Misha Hussain                                                    March 12, 2015sC

(Scroll down for links to press release and full report.)

DAKAR -- West Africa may lose up to $15 billion over the next three years due to the impact of the Ebola outbreak on trade, investment and tourism, according to a report by the United Nations.

The world's deadliest Ebola epidemic has killed almost 10,000 people in the three most affected countries of Guinea, Liberia and Sierra Leone, deepening poverty in one of the least developed parts of the world.

"The consequences of Ebola are vast," said Abdoulaye Mar Dieye, Africa director of the United Nations Development Programme (UNDP).

"Stigma and risk aversion have caused considerable amounts of damage, shutting down borders and indirectly affecting the economies of a large number of countries in the sub-region."

Read complete story

http://news.yahoo.com/ebola-could-cost-west-africa-15-billion-over-150805196.html;_ylt=AwrBJSCTtwFVoAIAda3QtDMD

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British Army medic with Ebola evacuated with two other suspected cases

THE TELEGRAPH  by  Victoria Ward and Ben Farmer   March 12, 2015  

A female Army medic who has caught Ebola while working in Sierra Leone is being flown back to Britain by the RAF, along with two workers who have been in close contact with her.

              Beatrice Yordoldo (Seated), an Ebola patient, poses for photographs with medical staff  Photo: AFP

Two further health workers who have been exposed to the unnamed soldier are being tested in Sierra Leone and could be evacuated later...

The woman is the third British health care worker confirmed to have caught the deadly virus...

Justine Greening, the Development Secretary, said the checks on the four other workers were "purely precautionary" after they had close contact with the female patient.

http://www.telegraph.co.uk/news/worldnews/ebola/11466376/British-Army-medic-with-Ebola-being-flown-back-to-UK.html

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Liberian Leader Concedes Errors in Response to Ebola

NEW YORK TIMES  by Rick Gladstone                                                                   March 12, 2015 

The president of Liberia acknowledged on Wednesday that she had erred in ordering a tough security crackdown at the height of the Ebola crisis last year, describing the deadly virus as an “unknown enemy” that had frightened her.

Liberian President Ellen Johnson Sirleaf during a video address last Deceber to the Senate Foreign Relations Committee

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New Ebola drug trial starts in Sierra Leone

SCIENCE By Kai Kupferschmidt                                                                       March 11, 2015

Researchers in Sierra Leone today started a new phase II trial of an experimental drug in Ebola patients. The first participant received an injection of the therapeutic, called TKM-Ebola, this morning at an Ebola treatment unit in Kerry Town. The trial may expand to other sites; the study team hopes to have an answer fast so that it can either move on to another drug or start a phase III study of TKM-Ebola.

Produced by Tekmira Pharmaceuticals in Burnaby, Canada, TKM-Ebola is made of synthetic, small interfering RNAs packaged into lipid nanoparticles. The RNAs target three of Ebola’s seven genes, blocking the virus’s replication. TKM-Ebola has been shown to work well in monkeys; the efficacy trial in humans is only starting now because there was not enough of the drug available earlier. Also, the RNAs have been adapted to the strain circulating at the moment.

The study does not have a placebo arm; all patients at the trial site are eligible for the drug, and researchers hope to determine whether it works by comparing them with patients treated elsewhere.

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No new Ebola cases in Liberia for more than two weeks: WHO

AFP                                                                                                                       March 11, 2015

Geneva  - No new case of the deadly Ebola virus has been registered in Liberia since February 19, the World Health Organization said Wednesday, also hailing positive signs in Sierra Leone and Guinea.

                      A man walks past an Ebola campaign banner with the new slogan "Ebola Must GO" in Monrovia

Liberia, long the hardest-hit country in the Ebola epidemic that has killed nearly 10,000 people in west Africa, "has now gone well over two weeks without a new reported case," said Bruce Aylward, who heads WHO's Ebola response....

The outlook was less positive in the other countries affected by the outbreak, Guinea and Sierra Leone, although Aylward highlighted positive signs there too.
Read complete story.
http://news.yahoo.com/no-ebola-cases-liberia-more-two-weeks-175855158.html;_ylt=AwrBJR9j5gBVAQYArDLQtDMD

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Waning interest is biggest risk in race to overcome Ebola: WHO

REUTERS     by Tom Miles                                                                                        March 11, 2015

GENEVA -Waning interest in Ebola could jeopardize efforts to stamp out the world's worst recorded outbreak of the disease, the World Health Organization said on Wednesday.

Nameplates are seen at a cemetery for victims of Ebola virus in Suakoko, Liberia, March 11, 2015.  Reuters/James Giahyue

Case numbers have fallen to a low level and it should be possible to stop transmission by mid-year, but the disease is "not waning" and it is much too early to assume the outbreak will end, said WHO Assistant Director General Bruce Aylward.

"We talk often about how steep the drop in cases has been. The only thing that has dropped more quickly and more steeply is the new contributions in financing," he told reporters in Geneva. 

...the failure to make further inroads is "alarming", Aylward said.

"Getting from here to zero is going to require another reinvestment (in the drive to tackle the outbreak)."

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Why we’re still waiting on an Ebola vaccine

Researchers are scrambling to start trials before the outbreak fades, but establishing faith in vaccines will take time

AL JAZEERA AMERICA  by

FREETOWN, Sierra Leone — Since Ebola hit this coastal city last summer, nurses at Connaught Hospital have put their lives on the line by working with patients at risk of the deadly disease. Now researchers aim to recruit them as well as ambulance drivers and other hospital staff as subjects in one of the largest Ebola vaccine trials to date.

But just a few weeks before the trial begins enrollment, many health care workers are voicing discomfort about the shot. “It would be really good to have a vaccine, but we’re scared because it’s new,” said Kadiatu Nubieu, a nurse at Connaught.

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A panel of independent experts to assess WHO's response in the Ebola outbreak

WHO PRESS RELEASE                                                March 10, 2015

The WHO Director-General has commissioned a panel of outside independent experts to undertake an assessment on all aspects of WHO’s response in the Ebola outbreak. This is in response to a resolution passed during the Ebola Special Session of the Executive Board in January 2015.

Dame Barbara Stocking will chair the panel. She was formerly Chief Executive of Oxfam GB (2001-13) and during this time led major humanitarian responses. Currently she is President of Murray Edwards College, University of Cambridge, UK.

The other panel members are: Professor Jean-Jacques Muyembe-Tamfun, Director-General of the National Institute for Biomedical Research, Democratic Republic of the Congo; Dr Faisal Shuaib, Head of the National Ebola Emergency Operations Center, Nigeria; Dr Carmencita Alberto-Banatin, independent consultant and advisor on health emergencies and disasters, Philippines; Professor Julio Frenk, Dean of the Faculty, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA; and Professor Ilona Kickbusch, Director of the Global Health Programme at the Graduate Institute of International and Development Studies, Geneva, Switzerland.

The panel will present a first progress report on its work to the 68th World Health Assembly in May 2015.

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