Research

NATIONAL PUBLIC RADIO  by Michaeleen Doucleff              Jan. 2, 2015

...Scientists think bats likely triggered the entire Ebola epidemic in West Africa....

So now the big question is: Where else in the world is Ebola hiding out in bats? Where could the next big outbreak occur?

Ecologists found signs of Ebola in a Rousettus leschenaultii fruit bat. These bats are widespread across south Asia, from India to China. Kevin Olival/EcoHealth Alliance

.. ecologist Kevin Olival at EcoHealth Alliance in New York City... hunts down another virus in bats, called Nipah. In humans, it causes inflammation in the brain and comas....

Nipah has outbreaks every few years in Bangladesh. So Olival went there back in 2010 and captured a bunch of bats. Many had signs of Nipah in their blood. Others had something surprising: "There's antibodies to something related to Ebola Zaire."

WASHINGTON POST by  Rachel Feltman                      Dec. 29, 2014

Pharmaceutical company Roche announced Monday that the U.S. Food and Drug Administration had provided an Emergency Use Authorization -- a sort of pre-approval for use in particularly bad outbreaks -- for a new kind of Ebola test.

This isn't the first test to get this kind of approval during the 2014 outbreak of the Zaire strain of Ebola, which has killed more than 7,500 people to date and is still an ongoing crisis in parts of West Africa.... 

So it's no surprise that Swiss company Roche has put its version of a rapid test forward. The LightMix Ebola Zaire rRT-PCR Test works in about three hours, and is designed for Roche's testing consoles.

REUTERS                                                              Dec. 24, 2014

ACCRA—Medical detective work will be the next big phase in the fight against Ebola when the United Nations deploys hundreds of health workers to identify chains of infection as the virus passes from person to person, top U.N. health workers said.
Health workers bury the body of a suspected Ebola victim at a cemetery in Freetown, Dec. 21, 2014.

The health teams will travel to each district and region of Guinea, Sierra Leone and Liberia, the three countries at the center of the epidemic, to trace who each infected person has potentially contacted.

The effort will run in parallel with measures to minimize the spread of infection, such as treating all Ebola patients in specialized centers and burying all victims safely.

But Phase Two of the plan is to contain the virus by understanding its lines of transmission, said World Health Organization Director-General Margaret Chan.

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BBC     By Smitha Mundasad                                Dec. 22, 2014
The first-ever trial of an Ebola vaccine in Africa shows promising initial results, according to a report in the Lancet medical journal.

Scientists say it is a crucial step as other vaccines have shown lower levels of protection in African populations.

Tests involving Ugandan and American volunteers reveal the vaccine is so far safe and generates an immune response in both populations.

It provides reassurance for other trials currently underway, they say.

No proven vaccine exists to prevent people from getting the disease, though several trials are underway.

Researchers from the National Institutes of Health tested this experimental vaccine on healthy adults in Uganda, having first trialled it in the United States.

Dr Julie Ledgerwood, the lead researcher, said: "This is the first study to show comparable safety and immune response of an experimental Ebola vaccine in an African population.

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http://www.bbc.com/news/health-30577776