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This working group is focused on discussions about health.

The mission of this working group is to focus on discussions about health.

Members

Corey Watts John Girard jonber37 Kathy Gilbeaux Lisa Stelly Thomas Maeryn Obley
mdmcdonald MDMcDonald_me_com mike kraft

Email address for group

health-us@m.resiliencesystem.org

Ebola in West Africa at One Year — From Ignorance to Fear to Roadblocks

Editorial urging U.S. academic medical centers to do more to fight Ebola
in West Africa

NEW ENGLAND JOURNAL OF MEDICINE                            Dec. 24, 2014
By Jeffrey M. Drazen, M.D., Edward W. Campion, M.D., Eric J. Rubin. M.D., Ph.D., Stephen Morrissey, Ph.D., and Lindsey R. Baden, M.D.

... As the Ebola outbreak has burned its way deep into Guinea, Liberia, and Sierra Leone, in one of the worst acute public health crises in 50 years, our academic medical centers have sat largely on the sidelines.

...The leaders of academic medical centers that have put roadblocks in the path of those wishing to serve need to rethink their priorities. They should be making it easier, not harder, for altruistic physicians, nurses, and other health care providers to help care for the sick and control the Ebola epidemic in West Africa. ... Something is wrong when some of the greatest health care centers in the world are not helping in the fight against this disastrously dangerous threat to human health. We ask the leaders of every medical center in the country to figure out how to make it possible for their staff, and even qualified trainees, to help on the ground in West Africa.

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CDC reports potential Ebola exposure in Atlanta lab

THE WASHINGTON POST  by Lena H. Sun and Joel Achenbach       Dec. 24, 2014

One scientist may have been exposed to the Ebola virus and as many as a dozen others are being assessed for potential exposure at a lab of the Centers for Disease Control and Prevention in Atlanta, agency officials said Wednesday.

Experiments with deadly viruses such as Ebola have to be performed in biosafety level or BSL-4 laboratories, for the highest level on containment. (Tim Brakemeier/AFP/Getty Images)

The potential exposure took place Monday when scientists conducting research on the virus at a high-security lab mistakenly put a sample containing the potentially infectious virus in a place where it was transferred for processing to another CDC lab, also in Atlanta on the CDC campus.

The technician has no symptoms of illness and is being monitored for 21 days. Agency spokeswoman Barbara Reynolds said others who entered the lab have been contacted and will be assessed for possible exposure by CDC clinicians. She said the number of exposures could be much less than a dozen.

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Ebola raises profile of blood-based therapy

NATURE     by  Delcan Butler                                                                                        Dec. 23, 2014

With no drugs available to treat Ebola, eyes are turning to a therapy that had largely been relegated to the history books: transfusing patients with blood plasma donated by survivors, which contains antibodies against the virus.

Survivors of Ebola carry antibodies that might be used to save the lives of those infected with the virus. Michel du Cille/The Washington Post via Getty Images

Clinical trials of convalescent plasma therapy (CPT) have started in the past few weeks in Liberia, and are due to begin soon in Guinea and Sierra Leone. If the therapy saves lives, the approach could quickly be scaled up.

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C.D.C. Head Says Fight on Ebola Will Be Long

NEW YORK TIMES by Denise Grady                             Dec. 23, 2014
There are reasons for both hope and continued worry about the Ebola epidemic in West Africa, Dr. Thomas R. Frieden, director of the Centers for Disease Control and Prevention, said on Monday.

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Ebola vaccine 'promising in African populations'

BBC     By Smitha Mundasad                                Dec. 22, 2014
The first-ever trial of an Ebola vaccine in Africa shows promising initial results, according to a report in the Lancet medical journal.

Scientists say it is a crucial step as other vaccines have shown lower levels of protection in African populations.

Tests involving Ugandan and American volunteers reveal the vaccine is so far safe and generates an immune response in both populations.

It provides reassurance for other trials currently underway, they say.

No proven vaccine exists to prevent people from getting the disease, though several trials are underway.

Researchers from the National Institutes of Health tested this experimental vaccine on healthy adults in Uganda, having first trialled it in the United States.

Dr Julie Ledgerwood, the lead researcher, said: "This is the first study to show comparable safety and immune response of an experimental Ebola vaccine in an African population.

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http://www.bbc.com/news/health-30577776

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U.S. to Complete Ebola Treatment Units in Liberia by End of December

WALL STREET JOURNAL by Junian E. Barnes and Felicia Schwartz                                                 Dec. 22, 2014
WASHINGTON—The U.S. will complete the last of its Ebola treatment units in Liberia by the end of December, setting the stage for the military to decide next month whether to send some service members home or send them to another West African country, the top U.S. commander in Liberia said Monday.

The U.S. will decide by mid-January whether to redeploy troops to Sierra Leone or Guinea or simply further shrink the size of the military mission in Liberia, Maj. Gen. Gary Volesky, the commander of the military’s Ebola task force, said in an interview with The Wall Street Journal.

The military task force has been involved in the building of 14 treatment units, in addition to the treatment unit completed before the 101st Airborne Division arrived. ...

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http://www.wsj.com/articles/u-s-to-complete-ebola-treatment-units-in-liberia-by-end-of-december-1419285448

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Chris Coons Travels To Liberia For Ebola Follow-Up

HUFFINGTON POST     by  Arthur Delany                                                                      Dec, 22, 2014

WASHINGTON -- Sen. Chris Coons (D-Del.) traveled to the West African nation of Liberia this week, partly to remind the American people that an Ebola epidemic is still going on, Coons told reporters Monday.

 

                     Sen. Chris Coons (D-Del.) elbow-bumps an Ebola survivor in Liberia. | Chris Coons Flickr | Flickr

"My hope was to remind the American people that this is an investment that helps keep the world safe, not just help Liberians, although helping Liberia is a worthy goal in and of itself," Coons said on a conference call in response to a question from HuffPost.

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Tekmira Inks Deal to Test New Ebola Drug in Humans

GENOMEWEB                                                                                                                        Dec. 22, 2014
NEW YORK -- Tekmira Pharmaceuticals announced today that it has signed a deal that will support the clinical testing of its experimental Ebola therapy designed against the strain of the virus behind the outbreak in West Africa.

Tekmira has long been developing an siRNA-based Ebola drug called TKM-Ebola, but a Phase I study of that agent was suspended by US regulators until the company could provide additional safety data. Earlier this year, Tekmira management indicated that that trial might not restart as early as anticipated since the firm had begun focusing on a version specifically for the Guinea strain of the Ebola virus, which is driving the ongoing outbreak.

Tekmira said it has now inked a manufacturing and clinical trial agreement with the University of Oxford to provide the new drug, called TKM-Ebola-Guinea, for clinical trials in West Africa. The university is the representative of the International Severe Acute Respiratory and Emerging Infection Consortium, which will be testing TKM-Ebola-Guinea in infected individuals with funding from the Wellcome Trust.

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DoD extends review of Ebola quarantine policy

MILITARY TIMES By Andrew Tilghman                                                                                Dec. 19, 2014
Thousands of troops deployed to West Africa to help contain the Ebola virus will have to wait a few more weeks to find out whether the policy of 21-day quarantines after their redeployment will continue, military officials said.

The Pentagon has granted an extension on the deadline for reviewing the controversial rule requiring a 21-day, post-deployment quarantine. The review will now be completed by Jan. 30, 2015.

When Defense Secretary Chuck Hagel announced the quarantine on Oct. 29, he ordered military officials to conduct a review within 45 days to determine whether it was effective and necessary.

That review was due on Dec. 12, but Hagel granted a seven-week extension following a request from the chairman of the Joint Chiefs, Army Gen. Martin Dempsey.

Read complete story.
http://www.militarytimes.com/story/military/pentagon/2014/12/19/ebola-quarantine-review/20637663/?utm_source=December+22+2014+EN&utm_campaign=12%2F22%2F2014&utm_medium=email

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Report: US unprepared for disease outbreaks despite billions spent

THE HILL            by Sarah Ferris                                 Dec.18, 2014

Major gaps exist in the country’s capacity to handle public health crises like Ebola despite massive government spending over the last decade, according to a new report.

Inadequate funding, weak leadership and uneven standards are all putting Americans at risk for infectious diseases, according to an extensive 112-page report by the Trust for America’s Health and Robert Wood Johnson Foundation

“Much of the nation’s approach to fighting infectious disease has not been modernized in decades,” the report warns. “There have been troubling errors, lapses and scrambles to recreate practices and policies that were supposed to have been long considered and well established.”

Nearly half of states received failing scores on the National Health Security Preparedness Index, which measures states’ health spending, vaccination rates, food testing and HIV/AIDS prevention....

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