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Leading from behind the curve on Ebola

- September 15 2014 - washingtonpost.com

The nation of Liberia — founded by liberated American slaves with support from Henry Clay, Daniel Webster and James Monroe — is not unacquainted with suffering. Two civil wars in the period from 1989 to 2003 and decades of economic mismanagement caused an 80 percent decline in per capita GDP — perhaps worse than any country since World War II. Warlords reduced Liberia’s infrastructure to rubble. In the 15 years following 1991, there was no electricity in the country except for private generators.

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Rains complicate delivery of Ebola supplies in West Africa

 

Mon Sep 29, 2014 

WASHINGTON - The rainy season in West Africa is compounding difficulties in getting supplies delivered and new treatment centers built as donors rush to isolate people infected with the deadly Ebola virus and stop its rapid spread, U.S. officials said.

Nancy Powell, newly appointed as the U.S. State Department's envoy to coordinate its Ebola response, said the top priority is to isolate as many people as quickly as possible. But that faces significant logistical hurdles.

"Infrastructure challenges in the rainy season is one of the biggest difficulties. And you add the rain and getting materials out of the capital and it is very difficult," Powell said in a news briefing last week.

The July to September rainy season is coming toward its end, but October is known for heavy thunderstorms that can drench the region and turn roads to mud.

Eric Talbert, executive director of Emergency USA which has opened a 22-bed Ebola treatment center in Goderich, outside the capital of Freetown in Sierra Leone, said the downpours complicate getting supplies along unpaved single track roads that are washed out by the heavy rains..

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Situation Report Overview by the Associated Press

 

Bulk of promised global aid has yet to materialize on the ground

 The Associated Press Posted: Sep 28,  Updated: Sep 28, 2014 1:10 PM ET

  Doctors are in short supply. So are beds for patients. Six months after the Ebola outbreak emerged for the first time in an unprepared West Africa and eventually became the worst-ever outbreak, the gap between what has been sent by other countries and private groups and what is needed is huge.

Even as countries try to marshal more resources, those needs threaten to become much greater, and possibly even insurmountable....

Beds are filling up as fast as clinics can be built. Ambulance sirens blare through standstill traffic. Often, there is nowhere to take the sick except to "holding centres" where they await a bed at an Ebola treatment facility.

The virus has killed almost 3,000 people and infected more than 6,200 in Liberia, Sierra Leone, Guinea, Nigeria and Senegal.

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Overview of U.S.Defense Department activities against Ebola, including testing vaccine candidate

By Cheryl Pellerin

DoD News, Defense Media Activity

WASHINGTON, Sept. 26, 2014 – The Defense Department has made critical contributions to the fight against the deadly Ebola outbreak in West Africa, and today Defense Secretary Chuck Hagel described additional ways the Pentagon is helping in the broader battle against infectious disease outbreaks of the future.

He spoke at a gathering of top government and military officials and infectious disease experts from 44 countries here to attend the Global Health Security Agenda, or GHSA, Summit hosted by President Barack Obama.

Hagel said ...the department also is accelerating the manufacture of potential treatments and starting clinical trials for a vaccine candidate and it has received approval to begin safety testing for one [Ebola] vaccine candidate that will be conducted at the Walter Reed Army Institute of Research.”

...The DoD Cooperative Threat Reduction Program is providing unique resources and expertise to enhance detection and surveillance, Hagel said, and all department assets will help civilian responders contain Ebola's spread and mitigate its economic, social and political fallout.

For fuller description of the Defense Department's activities to counter Ebola see link to the full article:

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Doctor in Liberia reports some success in treating Ebola with an HIV drug

The Washington Post Follow-up to the original CNN report        Oct. 2, 2014

Since the original CNN interview, Logan has been in contact with Dr. Fauci. "I can't say it's a good idea or bad idea," Fauci told The Post this week. "It's one of those things where you're in a situation where you have no therapy, so you look for things that might be available."

Fauci said National Institutes of Health researchers have tested lamivudine's reaction to Ebola in test tubes. There was no response; but Fauci said researchers will adjust some levels and try it again "to see if there's even slight activity against Ebola."

If there is, he said, NIH would consider going to the trial stage.

It makes sense to consider lamivudine as a potential Ebola treatment: It belongs to a group of drugs known as nucleoside analogs, which interfere with the replication processes of certain viruses, Fauci explained.

See Washington Post report

http://www.washingtonpost.com/news/to-your-health/wp/2014/10/02/a-liberian-doctor-is-using-hiv-drugs-to-treat-ebola-victims-the-nih-is-intrigued/

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U.S. Chamber of Commerce Foundation - Ebola Outbreak Coordination Conference Call

                    

uschamberfoundation.org

Event: Corporate Citizenship Center - Ebola Outbreak Coordination Conference Call
Friday, September 26, 2014 - 2:00pm

The U.S. Chamber of Commerce Foundation Corporate Citizenship Center (CCC) hosted a conference call on Friday, September 26 at 2:00 p.m. Eastern Time to discuss the Ebola outbreak in West Africa.

Over the past six months, an Ebola outbreak has affected five countries in West Africa (Guinea, Liberia, Nigeria, Senegal, and Sierra Leone).  The current outbreak is unprecedented in scale and geographical reach: the present West Africa outbreak has a higher caseload than all other previous Ebola crises combined.  Worse yet, the United Nations reports that the outbreak continues to accelerate, with almost 40% of the total cases occurring in the past 21 days.

CCC’s Ebola coordination conference call will provide updated information on the humanitarian response and the efforts to contain the disease.  It will also detail ways that the business community can help.

CLICK HERE - Listen to the Call Archive

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A Professor in U.S. is Telling Liberians that the Defense Department ‘Manufactured’ Ebola

      

An Ebola sign placed in front of a home in the West Point slum area of Monrovia, Liberia, on Sept. 25, 2014. (EPA/AHMED JALLANZO)

washingtonpost.com - by Terrence McCoy - September 26, 2014

. . . As those military doctors and officials begin what will be a difficult task, among the challenges they face are rumors that spread fear — fear of Ebola, fear of quarantine measures and fear of doctors. Already, several medical workers have been murdered in Guinea — throats slit, bodies dumped in a latrine. Then six Red Cross volunteers were attacked earlier this week while they tried to collect the body of an Ebola victim.

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Tourists advised to avoid Ebola zones of West Africa

NEW YORK TIMES      September 26, 2014

By

 .... The C.D.C. has issued a Watch Level 3 warning (“avoid nonessential travel”) for Guinea, Sierra Leone and Liberia, and a Level 2 warning (“practice enhanced precautions”) for Nigeria and the Democratic Republic of Congo.

Tourists should not visit these areas. The C.D.C. has recommended that foreign exchange, research and other education-related travel be postponed until further notice. Although the situation can change rapidly, there is now no risk of contracting Ebola in countries in West Africa without reported cases.

Anyone in the affected countries who gets a fever and symptoms like headache, muscle pain, vomiting, diarrhea, stomach pain or unexplained bleeding or bruising should avoid all contact with others and travel immediately by private transportation to a doctor’s office or hospital.

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Ebola: a Failure of International Collective Action

The Lancet, Volume 384, Issue 9949, Page 1181, 27 September 2014
doi:10.1016/S0140-6736(14)61606-8
 
Published Online: 10 September 2014
 
Mit Philips, Aine Markham

The Lancet Editorial (Aug 23, p 637)1 sums up the collective failure to respond in a manner that might have avoided or at least limited the scale of the present Ebola epidemic.

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