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UN: At Least 50 Ebola Hotspots Remain, but New Cases Falling

ASSOCIATED PRESS   By EDITH M. LEDERER                                                         Jan. 15, 2015

UNITED NATIONS --At least 50 Ebola hotspots remain in the three hardest-hit West African countries but new cases are declining and the deadly disease will be defeated, the U.N.'s Ebola chief said Thursday.

The latest report from the World Health Organization showing reductions in Guinea, Liberia and Sierra Leone "is very good news," Dr. David Nabarro said in an interview with The Associated Press.

In the week ending Jan. 11, WHO said Guinea reported its lowest weekly total of new Ebola cases since mid-August. Liberia had its lowest total since the first week of June and no confirmed new cases for the final two days of the week. And new cases in Sierra Leone declined for a second week to the lowest level since the end of August.

But Nabarro cautioned that "there are still numbers of new cases that are alarming, and there are hotspots that are emerging in new places that make me believe there is still quite a lot of the disease that we're not seeing."

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Ebola Cases Drop Off in West Africa

NBC NEWS     by Maggie Fox                                                                             Jan. 14, 2005
The number of new Ebolacases is starting to drop off in the three worst-hit West African countries, and Liberia has only reported 48 cases in the past three weeks, the World Health Organization reported Wednesday.

Guinea and Liberia both reported the fewest new cases since August, WHO says in its latest daily look at Ebola statistics. Sierra Leone is still suffering badly, with 769 new cases over the past 21 days, but that's a decline in reported cases.

"Sierra Leone has now reported a decline in case incidence for the second week running, and recorded its lowest weekly total of new confirmed cases since the week ending 31 August 2014," WHO said.

Overall, 21,261 people have been infected in this ongoing epidemic of Ebola, and 8,414 have died, WHO says.

http://www.who.int/csr/disease/ebola/situation-reports/en/

Ebola Situation report

WHO                                                                                         Jan. 14, 2015

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Ebola crisis update - 13th January 2015--MSF

 MEDECINS SANS FRONTIERS                                                                       Jan. 13, 2015

In September, 2014, MSF called for states with biological-disaster response capacity to urgently dispatch human and material resources to West Africa, all three of the worst-hit countries have received some assistance from the international community. But foreign governments have focused primarily on financing or building Ebola case management structures, leaving staffing them up to national authorities, local healthcare staff and NGOs.

Across the region, there are still not adequate facilities for isolating and diagnosing patients where they are needed. Other elements that are essential to an Ebola response – such as awareness-raising and community acceptance, safe burials, contact tracing, alert and surveillance, access to health care for non-Ebola patients – are still lacking in parts of West Africa.

Read complete report.

http://www.msf.org/article/ebola-crisis-update-13th-january-2015

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CDC director 'confident' can get to zero Ebola cases

REUTERS                                                                         Jan. 9, 2015

(Two stories. Scroll down.)

WASHINGTON --The director of the U.S. Centers for Diseases Control and Prevention said on Tuesday he was "confident" that the Ebola outbreak ravaging West Africa can be brought under control but that "we are by no means out of the woods."

Speaking at a breakfast meeting in Washington with public health officials and lawmakers, Dr. Tom Frieden said it is vital that every case of the disease is eliminated.

"I remain very confident we can get to zero cases in this epidemic if we continue the way we're going and nothing unexpected happens," Frieden said.

http://www.reuters.com/article/2015/01/13/us-health-ebola-frieden-idUSKBN0KM1KG20150113

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USAID: Eyes on Guinea as Liberia, Sierra Leone improve on Ebola

The rate of new Ebola cases in Liberia has plunged, Sierra Leone is beginning to turn the corner in dealing with the deadly virus and health officials are now focused on Guinea, a USAID official said on Tuesday.

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After Ebola, WHO blames governments and seeks more clout

REUTERS   by Tom Miles                              Jan. 13, 2015

GENEVA - The World Health Organization says governments flouted their obligations during the Ebola crisis and wants more power to tackle health emergencies in future, documents published by the international agency showed on Monday.

The Geneva-based U.N. health organisation has been heavily criticised for its slow response to the Ebola epidemic, which has now killed at least 8,371 people out of more than 21,000 cases in Liberia, Sierra Leone and Guinea.

The WHO promised in October to publish a full review of its handling of the outbreak once the epidemic was under control.

But it has not yet done so.

The documents submitted to its 34-nation Executive Board said governments had put International Health Regulations that cover public health risks and disease outbreaks at risk through actions such as closing borders and discriminating against travellers from Ebola-affected countries.

Read complete story.

http://af.reuters.com/article/topNews/idAFKBN0KM0CU20150113?pageNumber=1&virtualBrandChannel=0

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WHO experts chart next steps for Ebola vaccine trials

CENTER FOR INFECTIOUS DISEASE AND POLICY RESEARCH     by Lisa Schnirring                                 Jan. 9, 2015

The next steps in testing Ebola vaccines as well as a picture of how they might be used in West Africa's outbreak region became clearer today as officials from the World Health Organization (WHO) shared the outcome of yesterday's (Thursday's) high-level meeting in Geneva.

Large phase 3 trials in West Africa's outbreak setting will be next up to see if the vaccines work, with the studies designed to collect more safety data, a task usually covered in phase 2 trials, experts involved in the meeting said today at a WHO media telebriefing. However, as Ebola infections drop off in the outbreak region, scientists face a closing window of opportunity to see how the vaccines perform in a real-life setting.

Experts also signaled a possible role for two Ebola vaccine formulations: a single-dose vaccine providing shorter-term immunity that could be used to tamp down Ebola flare-ups and a prime-boost vaccine that may provide more durable immunity and could be used for other immunization strategies.

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2014 Ebola Outbreak in West Africa - Case Counts

Case Counts: Ebola

CDC                                                                                                                   Jan. 12, 2015

Case counts updated in conjunction with the World Health Organization updates and are based on information reported by the Ministries of Health.

As of January 10, 2015 (Updated January 12, 2015)

See complete statistics report.

http://www.cdc.gov/vhf/ebola/outbreaks/2014-west-africa/case-counts.html

 

2014 Ebola Outbreak in West Africa - Cumulative Reported Cases Graphs

See graphs.

http://www.cdc.gov/vhf/ebola/outbreaks/2014-west-africa/cumulative-cases-graphs.html

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Ebola Hampering Household Economies across Liberia and Sierra Leone

Latest surveys point to declines in employment, food insecurity, and long-term welfare concerns

THE WORLD BANK                                                       Jan. 12, 2015

WASHINGTON-- The socio-economic impacts of Ebola in Liberia and Sierra Leone are far-reaching and persistent, according to two new World Bank Group reports. Both countries continue to experience job losses, despite their differing health outlooks. These impacts have not been limited to the areas where infections have been the highest, which points to economy-wide slowdowns. As a result, many households have been forced to take short-term actions to cope, which can have substantial long-term effects on welfare.

The Ebola virus itself must be eradicated- this is the number one priority,” said Ana Revenga, Senior Director for Poverty at the World Bank Group. “But its socio-economic side effects put the current and future prosperity of households in Liberia and Sierra Leone at high risk. We must pay careful attention to those who are most vulnerable to both health and economic shocks, and ensure that they are supported throughout and after the crisis.

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Health 2 Leading Ebola Vaccines Appear Safe, Further Tests Starting

ASSOCIATED PRESS  by Maria Cheng                                                                          Jan. 9, 2015
LONDON --The World Health Organizationsays the two leading Ebola vaccines appear safe and will soon be tested in healthy volunteers in West Africa.

After an expert meeting this week, WHO said there is now enough information to conclude that the two most advanced Ebola vaccines ? one made by GlaxoSmithKline and the other licensed by Merck and NewLink ? have "an acceptable safety profile."

In a press briefing on Friday, Dr. Marie-Paule Kieny, who heads WHO's Ebola vaccine efforts, said "the cupboard (for Ebola vaccines) is filling up rapidly."

She said further trials in healthy people in West Africa, including health workers, are scheduled to start soon. Kieny added several other vaccines were being developed in the U.S., Russia and elsewhere.

Read complete story.
http://abcnews.go.com/Health/wireStory/leading-ebola-vaccines-safe-tests-starting-28107527

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Ebola: vaccine trials can offer ‘signs of hope’ says UN health chief

UNITED NATIONS NEWS CENTRE                                Jan. 8, 2015

GENEVA--The United Nations World Health Organization (WHO) today convened in Geneva its second ever high-level meeting on Ebola vaccines access and financing, to review the current status of clinical trials and plans for Phase II and Phase III efficacy trials.

WHO mobile lab scientists at the crossing point between Guinea and Sierra Leone, two of the countries affected by the Ebola outbreak in West Africa. Photo: WHO/Saffea Gborie

“We are here to take stock, plan the next steps, and make sure that all partners are working in tandem. We all want the momentum and sense of urgency to continue,” Dr. Margaret Chan, Director-General of WHO said as she kicked off the meeting.

The most advanced candidate Ebola vaccine is scheduled to enter Phase III efficacy clinical trials in West Africa in January/February 2015, and if shown effective – will be available for deployment a few months later.

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