Investment in universal healthcare: Improving health systems in three Ebola-hit African countries would have cost a third of relief effort there, says new Save the Children report

THE GUARDIAN      by Lisa O'Connell                                                                   March 3, 015
Up to 30 countries are vulnerable to an Ebola-style epidemic, unless the world sits up and helps get urgent investment into universal healthcare, a report (pdf) has found.

Health workers who have returned from west Africa and colleagues based in the UK walk to Westminster in support of Save the Children’s campaign to strengthen health systems globally. Photograph: Jeff Moore/Save the Children

FORBES   by   David Kroll                                                                                          March 1, 2015

The widely-discussed antibody cocktail, ZMapp, is finally going to be tested under standardized, controlled conditions for its safety and efficacy in Ebola virus disease-infected patients in Liberia and, potentially, the United States.

Late Friday, the NIH National Institute of Allergy and Infectious Disease (NIAID) announced the launch of a randomized trial in up to 200 patient volunteers with confirmed Ebola virus infections.

The two-arm study will compare supportive standard of care with or without three intravenous infusions of ZMapp spaced three days apart. This is the same dosing regimen published in Nature that protected 18 of 18 monkeys when given up to five days after experimental infection.

LeafBio, the commercial arm of San Diego-based Mapp Biopharmaceutical, announced concomitantly that the FDA had approved their IND for this trial. The three antibodies that comprise ZMapp target both distinct and overlapping parts of the Ebola virus glycoprotein (GP) that it uses to infect humans.

 REUTERS By Daniel Flynn, James Harding Giahyue and Saliou Samb                              Feb. 27, 2015

The Radisson Blu chain opened the four-star hotel in April to cater for investors in one of Africa's fastest-growing economies. A month later, Ebola crossed the border from Guinea and those investors fled....

For months, Sierra Leone was cut off from the world amid panic at the worst recorded outbreak of the hemorrhagic fever, which has killed more than 9,500 people in Sierra Leone, Guinea and Liberia and infected over 23,500.

But with infection rates slowly declining, investors have begun to talk about post-Ebola reconstruction. Neves has noted the return of businessmen not seen since the hotel opened.

"They don't bring their teams. They just come to see what is going on and then they leave," he said, adding that 'business as usual' remains far off. "This will be a year focused on Ebola. First the fight to end Ebola and then reconstruction...."

Morbidity and Mortality Weekly Report (MMWR)

 CDC                                                                        Feb. 27, 2015

Outbreaks in remote areas posed a significant challenge to CHTs to mount an effective investigation and rapid response because of limited resources, personnel, and means to reach remote areas.

Read complete report.
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6407a7.htm?s_cid=mm6407a7_x