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The Next Victims of Ebola

The epidemic may be nearing “zero cases” — but it's still disrupting the delivery of vaccines for measles, polio, and other deadly childhood diseases.

FOREIGN POLICY                                                                                                    April 27, 2015

by Ellen Johnson Sirleaf, President of Liberia, and Seth Berkley,  President and CEO of the Gavi vaccine alliance

When the Ebola epidemic in West Africa comes to an end, it will be marked by two simple words: “zero cases.” But this momentous milestone will also signal the beginning of a new struggle as the long and difficult process of recovering from a crisis that has claimed more than 10,000 lives commences. Ebola has not only drawn attention to the vast gap that exists between rich and poor nations; it has widened that divide too, setting the people of Liberia, Sierra Leone, and Guinea even further back. The opportunity to narrow and ultimately close this gap cannot be neglected.

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UN Says It Will Try to Identify All Ebola Cases by June

ASSOCIATED PRESS by Maria Cheng                                                        April 28, 2015

LONDON — The World Health Organization says it aims to identify and isolate all new Ebola cases in West Africa by the end of May to stop the spread of the lethal virus before the rainy season.

In a new Ebola plan released on Tuesday, the U.N. health agency said it hopes to limit transmission of the virus to the coastal areas of Guinea, Liberia and Sierra Leone before the rainy season begins, normally in April or May.

WHO said the decline in Ebola's spread has "plateaued," partly due to "persistently high transmission" in Guinea and Sierra Leone. Officials say the rainy season will make it more difficult for responders to reach remote areas....

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Nine Ways We Are Beating the Ebola Epidemic in West Africa

THE HUFFINGTON POST by                  April 26, 2015
.. Addressing an Ebola epidemic of this scale has taken the international community on a journey never before walked. Previously tried and tested methods have been used as well as novel strategies, but the scale that has been required is unprecedented.

Rapid response medical team outside a mobile treatment facility
Nathalie MacDermott/Samaritan's Purse International Relief

It is also apparent that no 'one size fits all' approach can work - the approach must be multifactorial, addressing the problem at it's roots within the communities where the outbreaks occur, but also on a national level to provide large scale isolation of cases and interrupt transmission of the virus.

Below are nine ways in which we are beating the Ebola epidemic in West Africa:

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Ella Foundation announces key outcomes in Ebola vaccine research

BUSINESS STANDARD                                                                        April 27, 2015

HYDERABAD, India --Ella Foundation, which has taken up research for finding a potential vaccine for the deadly Ebola virus, today said it had successfully completed preliminary studies on the virus, which was responsible for high fatalities among humans in central Africa.

The Hyderabad-based foundation said it had completed the preliminary animal (with mice) experiments of the virus' glycoprotein with the targeted adenovirus, and the "immune response results have been good", which would be followed by toxicology tests and the subsequent clinical trials involving human beings.

Adenoviruses are responsible for respiratory infections, gastroenteritis, cystitis, and primary pneumonia in humans, and are therefore used as a clear target to understand the human immunity characteristics in laboratory. However, the efficacy of the vaccine is judged by the outcomes seen in human trials.

Read complete story.

http://www.business-standard.com/article/current-affairs/ella-foundation-announces-key-outcomes-in-ebola-vaccine-research-115042700631_1.html

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UN chief names new head of Ebola mission as outbreak calms

ASSOCIATED PRESS by Jonathan Paye-Layleh             April 25, 2015

MONROVIA, Liberia — The U.N. chief on Saturday appointed a new head of the emergency mission responding to West Africa’s Ebola crisis amid hopes that the world’s deadliest outbreak of the virus will soon come to an end.

A statement from Ban Ki-moon’s office said Peter Jan Graaff of the Netherlands will work closely with David Nabarro, the U.N.’s special Ebola envoy, in addressing an epidemic that has claimed more than 10,000 lives in the three hardest-hit countries: Liberia, Guinea and Sierra Leone.

Outgoing head Ismail Ould Cheikh Ahmed was appointed as special envoy to Yemen on Saturday.

Graaff had been serving since October as the U.N.’s Ebola crisis manager in Liberia, which has recorded more Ebola deaths than any other country.

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http://www.washingtonpost.com/world/africa/un-chief-names-new-head-of-ebola-mission-as-outbreak-calms/2015/04/25/46ba3320-eb84-11e4-8581-633c536add4b_story.html

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West Africa battles mystery of 'post-Ebola syndrome'

AFP    by Zoom Dosso                                                            April 24, 2015
Monrovia -- As the Ebola epidemic retreats across west Africa, international health authorities are turning their attention to the little understood long-term effects of the often-deadly virus on the survivors.

 There is little research on patients cured of the tropical fever, but the World Health Organization (WHO) has acknowledged that many are experiencing crippling complications long after walking out of treatment units.

Matshidiso Moeti, the WHO's new head in Africa, told AFP that Liberian survivors had been reporting a range of problems, including sight and hearing impairment.

"We need to be aware that (complications) may be occurring and pay attention when people are being treated in case there is something that can be done to help them," she told AFP in the Liberian capital Monrovia.

Read complete story.

http://news.yahoo.com/west-africa-battles-mystery-post-ebola-syndrome-034727521.html;_ylt=AwrC0CM1rDtVtDoA83rQtDMD;_ylu=X3oDMTByOHZyb21tBGNvbG8DYmYxBHBvcwMxBHZ0aWQDBHNlYwNzcg--

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Empowering local media can make the difference: 5 lessons from the Ebola crisis

DEVEX byAlison  Campbell                                                                          April 23, 2015

The Ebola crisis in West Africa was quickly recognized as being driven as much by misinformation and rumors as by weaknesses in the health care system. Mohamed Komah interviews an Ebola survivor at the Donka Ebola treatment center in Conakry, Guinea. Photo by: Internews

International response agencies invested significant resources in rolling out the Social Mobilization and Community Engagement drive, a wide-scale intensive social behavior change communication campaign. The result was a massive and rather poorly coordinated blast of messaging shared on billboards, in print, on radio and TV, through health outreach workers and community organizations, via SMS and call-in hotlines.

A preliminary assessment done by Internews in November found more than 300 types of social mobilization and messaging systems in the three worst-affected countries: Liberia, Guinea and Sierra Leone. This chaotic information landscape consisted mainly of information “out,” with little opportunity for community dialogue....

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Ebola outbreak likely driving malaria deaths: study

AFP                                                                                                             April 24, 2015
PARIS --The collapse of health services in three west African countries devastated by Ebola may have caused some 11,000 additional deaths from malaria, a preventable and curable disease, researchers said Friday.

Desinfected gloves dry at Elwa hospital in Monrovia, Liberia on September 7, 2014 (AFP Photo/Dominique Faget)

A further 3,900 deaths may have resulted from interruptions in the delivery of insecticide-treated bed nets, according to outbreak modelling data published in The Lancet on the eve of World Malaria Day.

This suggested the haemorrhagic fever outbreak "could have resulted in a comparable number of malaria deaths as those due to Ebola itself," said a statement issued by the medical journal.

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US regulators recall 10-minute Ebola test

AFP                                                                                April  23, 2015
Miami  - US regulators have issued an international recall for a 10-minute Ebola blood test made by a California-based company, saying it has not been proven to work and could put lives at risk.

"A recall has been issued for the LuSys Laboratories, Inc., Ebola Virus One-Step Test Kits because the FDA has not cleared or approved the kits for use or sale," said the Food and Drug Administration in a statement emailed to reporters on Thursday.

"The results obtained from these test kits have not demonstrated to be accurate and should not be used as in vitro diagnostic tests for Ebola infection."

Contacted by AFP, a company representative in San Diego said early trials have shown the test to be 86 percent accurate. The problem with the FDA came down to a labeling error, he said. The equipment had not been properly labeled "for research purposes only."

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http://news.yahoo.com/us-regulators-recall-10-minute-ebola-test-193530081.html;_ylt=AwrC1CmnSjlVNDsAZTDQtDMD;_ylu=X3oDMTByaWg0YW05BGNvbG8DYmYxBHBvcwM4BHZ0aWQDBHNlYwNzcg--

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Ebola survivors donate plasma to tackle outbreak

EUREKALERT                                                                           April 22, 2015
UNIVERSITY OF LIVERPOOL -- 
The first donations of plasma, from survivors of the Ebola epidemic in Sierra Leone, have been received by an international research team working to help tackle current and future disease outbreaks in West Africa.

The team, led by scientists at the University of Liverpool and colleagues at the College of Medicine and Allied Health Services, Ministry of Health, Sierra Leone, is investigating how plasma from Ebola survivors could help treat patients with the disease at the Ebola Treatment Unit, run by the 34th Regiment Military Hospital group in Freetown.

Dr Calum Semple, from the University's Institute of Child Health, and his collaborators developed a convalescent plasma protocol in readiness for an outbreak, such as Ebola, as part of the outbreak preparatory work of the International Severe Acute Respiratory and Emerging Infection Consortium.

The study is one of several being supported by the Wellcome Trust's platform for evaluating experimental Ebola therapeutics in West Africa.

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http://www.eurekalert.org/pub_releases/2015-04/uol-esd042215.php

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